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Among leukocytes, only monocytes and macrophages were found to be highly susceptible to an infection by influenza A virus. After infection, de novo viral protein synthesis was initiated but then interrupted after 4-6 h. Most macrophages died by apoptosis within 25-30 h. Before cell death, however, macrophages responded to influenza A virus with a high(More)
Sleep deprivation (SD) has enriched our treatment programme for major depression. SD has been demonstrated to modify different host defence activities. There is some evidence that there are reciprocal relationships between immune function and increased hypothalamic-pituitary-adrenocortical (HPA) axis activity in depression. We therefore investigated the(More)
The effect of daily repeated 10 min immobilization on the serotoninergic neurotransmission and serum corticosterone levels was studied. Male Lewis rats were immobilized for a 10 min period daily once or on 5 consecutive days. Serotoninergic neurotransmission was followed using differential in vivo pulse voltammetry with carbon fibre electrodes measuring(More)
In prior research on the future of aviation it was established that operators will have to work with highly automated systems. Increasing automation will require operators monitoring appropriately (OMA). OMA are expected to demonstrate the use of distinctly different monitoring phases (orientation, anticipation, detection, and recheck). Within these phases,(More)
The increasing complexity of automated systems requires teams of operators monitoring those systems appropriately. The present study examines the effect of teamwork on monitoring performance and monitoring behaviour. Participants' eye movements were recorded whilst they monitored an automatic process both alone and in a team. The data imply that teamwork(More)
The research project Aviator 2030 at the German Aerospace Centre (DLR) focuses on finding an optimal fit between technical innovations and human operators in future aviation. Due to the increase in automation, accurate and efficient monitoring poses a great challenge to future operators in aviation. As the DLR`s Department of Aviation and Space Psychology(More)
The effect of immobilization and light-dark cycle on the serotoninergic system of the n. raphe dorsalis and on the distribution of blood lymphocyte subpopulations was studied in the rat. As was shown by in vivo voltammetry, 10 min immobilization enhanced serotonin metabolism with a maximum 15 min after immobilization. The distribution of the blood(More)
In order to detect automation failures in time, operators are required to monitor automated systems efficiently. The present study analyzed eye movements to predict whether or not subjects would detect an automation failure. Eye movements were recorded whilst subjects were monitoring an automated system where automation failures sometimes occur. The data(More)
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