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- Bjørnar Ytrehus, Cathy S Carlson, Stina Ekman
- Veterinary pathology
- 2007
Osteochondrosis is a common and clinically important joint disorder that occurs in human beings and in multiple animal species, most commonly pigs, horses, and dogs. This disorder is defined as a… (More)
- Nicole Gerwin, Alison M. Bendele, Sonya S. Glasson, Cathy S Carlson
- Osteoarthritis and cartilage
- 2010
OBJECTIVE
During the development of disease-modifying osteoarthritis (OA) drugs, rat models of OA are frequently used for a first assessment of in vivo efficacy. The most efficacious compound in the… (More)
- Richard F. Loeser, Raghunatha R Yammani, +5 authors Shirley ShiDu Yan
- Arthritis and rheumatism
- 2005
OBJECTIVE
The receptor for advanced glycation end products (RAGE) binds multiple ligands, including S100 proteins, high mobility group box chromosomal protein 1 (HMGB-1), and AGEs, all of which are… (More)
- William Edmund Sonntag, Christy S. Carter, +9 authors Melinda L. Ramsey
- Endocrinology
- 2005
Disruption of the insulin/IGF-I pathway increases life span in invertebrates. However, effects of decreased IGF-I signaling in mammalian models remain controversial. Using a rodent model with a… (More)
- Cathy S Carlson, Donald J. Meuten, Daniel C Richardson
- Journal of orthopaedic research : official…
- 1991
This study was designed to examine the association of spontaneous lesions of osteochondrosis with vascular supply to epiphyseal cartilage, and to determine whether similar lesions could be… (More)
- Raghunatha R Yammani, Cathy S Carlson, Anne R. Bresnick, Richard F. Loeser
- Arthritis and rheumatism
- 2006
OBJECTIVE
S100 proteins have been implicated in various inflammatory conditions, including arthritis. The aims of this study were to determine whether chondrocytes produce S100A4 and whether S100A4… (More)
- Anna Petryk, Ryan M Anderson, +5 authors Michael B O'connor
- Developmental biology
- 2004
Extracellular modulators of cell-cell signaling control numerous aspects of organismal development. The Twisted gastrulation (Twsg1) gene product is a small, secreted cysteine-rich protein that has… (More)
- Kristin Olstad, Bjørnar Ytrehus, Stina Ekman, Cathy S Carlson, Nils Ivar Dolvik
- Journal of orthopaedic research : official…
- 2007
Material available for research into osteochondrosis (OC) in humans tends to represent chronic lesions. Comparative studies of early lesions in young animals are, therefore, important in clarifying… (More)
- Bjørnar Ytrehus, Cathy S Carlson, +4 authors Stina Ekman
- Bone
- 2004
Until recently, the cartilage canals of the epiphyseal growth cartilage have not been associated with any specific disease. However, data support the hypothesis that osteochondrosis could be related… (More)
Cartilage canals are temporary vessel-containing structures within the growth cartilage. The canals gradually regress with age in a process designated chondrification, where the content of the canals… (More)