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BACKGROUND Little is known about the combined effect of micronutrients and essential fatty acids on cognitive function in school-aged children. OBJECTIVE We assessed the effect of micronutrients, long-chain n-3 fatty acids, or both on indicators of cognitive performance in well-nourished and marginally nourished school-aged children. DESIGN Two 2-by-2(More)
BACKGROUND Fortification with multiple micronutrients has been shown to improve growth and cognitive performance among children in developing countries, but it is unknown whether higher concentrations are more effective than lower concentrations. OBJECTIVE We compared the effect of 2 different concentrations of a combination of micronutrients and n-3(More)
The present paper evaluates the most recent randomized controlled trials assessing the efficacy of n-3 LCPUFA supplementation (with or without n-6 LCPUFA) during pregnancy, lactation, infancy and childhood on visual and cognitive development. Available evidence suggests a beneficial effect of maternal n-3 LCPUFA supplementation during pregnancy and(More)
BACKGROUND Although multiple micronutrient interventions have been shown to benefit children's intellectual development, a thorough evaluation of the totality of evidence is currently lacking to direct public health policy. OBJECTIVE This study aimed to systematically review the present literature and to quantify the effect of multiple micronutrients on(More)
The purpose of this study was to find new evidence for phonological coding in written word recognition among deaf Dutch children. A lexical decision task was presented to 48 severely and profoundly deaf children aged from 6 years 8 months to 13 years 5 months, and a control group of Grade 1 hearing children matched on written word recognition. Sixteen(More)
Micronutrient deficiencies compromise the health and development of many school-age children worldwide. Previous research suggests that micronutrient interventions might benefit the health and development of school-age children and that multiple micronutrients might be more effective than single micronutrients. Fortification of food is a practical way to(More)
The authors evaluated the adequacy of an extensive adaptation of the American Kaufman Assessment Battery for Children, second edition (KABC-II), for 6- to 10-year-old Kannada-speaking children of low socioeconomic status in Bangalore, South India. The adapted KABC-II was administered to 598 children. Subtests showed high reliabilities, the(More)
The combination of theobromine and caffeine, methylxanthines found in chocolate, has previously been shown to improve mood and cognition. However, it is unknown whether these molecules act synergistically. This study tested the hypothesis that a combination of caffeine and theobromine has synergistic effects on cognition, mood and blood pressure in 24(More)
OBJECTIVES To review the impact of polyunsaturated fatty acids (PUFA) in reducing ADHD symptoms in children. METHODS Peer-reviewed experimental literature published from 1980 to Mai 2009 is consulted (Psychinfo, Medline, and resulting reference lists). RESULTS Placebo-controlled studies with ADHD or hyperactive children show no effects on behaviors or(More)
OBJECTIVES The objective is to evaluate possible mechanisms explaining the link between polyunsaturated fatty acid (PUFA) deficiencies and ADHD, based on findings from animal research. METHOD The authors consulted peer-reviewed publications from the last 10 years (Medline and resulting reference lists). RESULTS PUFA deficiency in rodents results in(More)
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