Catherine Rolland

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Obesity and its association with co-morbidities in Africa are on the rise. This systematic review examines evidence of obesity and its association with co-morbidities within the African continent. Comparative studies conducted in Africa on adults 17 years and older with mean body mass index (BMI) ≥ 28 kg/m(2) were included. Five electronic databases were(More)
BACKGROUND Adipose tissue functions as an endocrine organ by releasing adipokines which have important roles in the regulation of inflammation and insulin sensitivity. Although there is evidence of improvement in circulating levels of adipokines with weight loss, few studies relate such changes to specific diets. We investigated the effects of weight loss(More)
Polycystic ovary syndrome (PCOS) affects 2%-26% of women of reproductive age and is often accompanied by obesity. Modest weight loss reduces health risks and ameliorates effects of the syndrome. Weight loss interventions are mainly of short duration and have limited success. A systematic review of the literature was carried out to assess the efficacy of(More)
BACKGROUND Polycystic ovary syndrome (PCOS) affects between 2% and 26% of reproductive-age women in the UK, and accounts for up to 75% of anovulatory infertility. The major symptoms include ovarian disruption, hyperandrogenism, insulin resistance, and polycystic ovaries. Interestingly, at least half of the women with PCOS are obese, with the excess weight(More)
Very low-calorie diets (VLCDs) are an effective means by which to induce clinically significant weight loss. However, their acceptance by health care practitioners and the public is generally lower than that for other nonsurgical weight loss methods. Whilst there is currently little evidence to suggest they have any detrimental effect on hepatic and renal(More)
Polycystic ovary syndrome (PCOS) is variously reported to affect between 5% and 26% of reproductive age women in the UK and accounts for up to 75% of women attending fertility clinics due to anovulation. The first-line treatment option for overweight/obese women with PCOS is diet and lifestyle interventions. However, optimal dietary guidelines are missing,(More)
This paper introduces design principles of serious games which goal is to understand the player/learner decision process. The analytical dimension is the core of gameplay questions: what are the mechanics able to make the player aware of his behavior as a decision-maker? This research questions the video game as a tool to develop the reflexivity and put in(More)
  • Fabio Paternò, Academic Editors, C Calero, K Framling, O Greevy, A Lastovetsky +1 other
  • 2013
The purpose of this paper is to introduce the motivations behind end user development, discuss its basic concepts and roots, and review the current state of art. Various approaches are discussed and classified in terms of their main features and the technologies and platforms for which they have been developed. Lastly, the paper provides an indication of(More)
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