Catherine M. Woods

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OBJECTIVE To conduct a detailed analysis of hamstring injuries sustained in English professional football over two competitive seasons. METHODS Club medical staff at 91 professional football clubs annotated player injuries over two seasons. A specific injury audit questionnaire was used together with a weekly form that documented each clubs' current(More)
Purpose. To assess the pharmacokinetics and biodistribution of gentamicin, delivered as PulmoSpheres® formulations in rabbit serum and lung tissue following intratracheal instillation in a perflubron vehicle. Methods. Rabbits were anesthetized, intubated, and mechanically ventilated with O2(FiO2 = 0.50). Animals were then given 5 mg/kg gentamicin either(More)
AIM To conduct a detailed analysis of ankle sprains sustained in English professional football over two competitive seasons. METHODS Club medical staff at 91 professional football clubs annotated player injuries. A specific injury audit questionnaire was used together with a weekly form that documented each club's current injury status. RESULTS(More)
Purpose. Delivery of specific antibodies or immunoglobulin constructsto the respiratory tract may be useful for prophylaxis or active treatmentof local or systemic disorders. Therefore, we evaluated the utilityof lipid-based hollow-porous microparticles (PulmoSpheres™) as apotential delivery vehicle for immunoglobulins. Methods. Lipid-based microparticles(More)
1. The aim of this study was to define the P1 purinergic receptors that regulate spontaneous or adenosine-induced duodenal motor activity. 2. Spontaneous contractile activity was recorded isometrically from possum longitudinal duodenal muscle strips. Adenosine (0.5 micro M-1 mM) was administered noncumulatively and repeated after pretreatment with a P1(More)
OBJECTIVES To conduct a detailed analysis of preseason football injuries sustained in English professional football over two competitive seasons. METHODS Club medical staff at 91 professional football clubs annotated player injuries. A specific injury audit questionnaire was used together with a weekly form that documented each club's current injury(More)
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). Adhesion molecules play important roles in cell-cell and cell-extracellular matrix (ECM) interactions in inflammation. Blocking the interaction between inflammatory cells and vascular endothelia can prevent cell entry into tissues and harmful inflammatory(More)
The goals in this study were several-fold. First, to optimize the in vivo phage display methodology by incorporating phage pharmacokinetic properties, to isolate peptides that target the brain microvasculature, and then to build focused libraries to obtain structure activity relationship information in vivo to identify the optimal targeting motif. The blood(More)
Purpose. Spray-dried lipid-based microparticles (SDLM) serve as a platform for delivery of a wide variety of compounds including peptides, proteins, and vaccines to the respiratory mucosa. In the present study, we assessed the impact of IgG-mediated targeting to phagocytic cells of inactivated influenza virus formulated in SDLM, on subsequent immune(More)
Cytoplasmic structure and rates of cyclosis in trichomes from chilling-sensitive watermelon (Citrullus vulgaris L.), tomato (Lycopersicon esculentum Mill.) andEpiscia reptans plants and from chilling-resistant foxglove (Digitalis purpurea) andVeronica persica were examined with differential interference contrast optics (DIC) as the temperature of the(More)