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Background and objective: Hyperactivity of the brain renin–angiotensin (Ang) system has been implicated in the development and maintenance of hypertension. AngIII, one of the main effector peptides… Continue Reading
CONTEXT Apelin and vasopressin levels are regulated in opposite directions to maintain body fluid homeostasis. OBJECTIVE We thus assessed plasma apelin to copeptin ratios, with plasma copeptin… Continue Reading
CONTEXT Apelin and arginine vasopressin are antagonists in the regulation of body fluid and osmotic homeostasis. There are no data about apelin levels in patients with polyuria-polydipsia syndrome… Continue Reading
Objective: To assess the hemodynamic and hormonal effects, the safety and tolerability of QGC001, a brain aminopeptidase A inhibitor, in hypertensive patients compared to placebo. Design and method:… Continue Reading
La presente invention a pour objet un compose de formule generale (I), dans laquelle R1 represente une chaine alkyle, alkenyle ou alkynyle, ou un groupement cycloalkyle, ou (cycloalkyle)alkyle… Continue Reading