Catherine H Maclean

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CONTEXT Omega-3 fatty acids are purported to reduce the risk of cancer. Studies have reported mixed results. OBJECTIVE To synthesize published and unpublished evidence to determine estimates of the effect of omega-3 fatty acids on cancer risk in prospective cohort studies. DATA SOURCES Articles published from 1966 to October 2005 identified through(More)
BACKGROUND Although several agents are available to treat osteoporosis, the relative efficacy and toxicity of these agents when used to prevent fractures has not been well described. PURPOSE To compare the benefits in fracture reduction and the harms from adverse events of various therapies for osteoporosis. DATA SOURCES MEDLINE (1966 to November 2007)(More)
BACKGROUND Patient global ratings of care are commonly used to assess health care. However, the extent to which these assessments of care are related to the technical quality of care received is not well understood. OBJECTIVE To investigate the relationship between patient-reported global ratings of health care and the quality of providers' communication(More)
OBJECTIVE Previous studies suggest that poorer knowledge and expectations about surgical outcomes may be responsible for low rates of total knee replacement (TKR) among African American males. The goal of this study was to pilot test the scope, acceptability, and efficacy of an educational videotape and tailored TKR decision aid designed to reduce(More)
D ementia is defined by acquired, progressive impairment in two or more cognitive areas (for example, frontal executive function, mood, or memory) that is severe enough to render a person dependent on others. Dementia is a leading cause of disability among older adult patients; Alzheimer disease is the most common etiology. The prevalence of Alzheimer(More)
BACKGROUND While falls and urinary incontinence are prevalent among older patients, who sometimes rely on proxies to provide their health information, the validity of proxy reports of concern about falls and urinary incontinence remains unknown. METHODS Telephone interviews with 43 consecutive patients with falls or fear of falling and/or bothersome(More)
V ision impairment is common in elderly people, and it increases with age. Population-based studies report functional visual impairment 1,2 in 4% to 7% of persons aged 71 to 74, 16% of persons aged 80 and older, and 39% of persons aged 90 and older. 3 Similarly, the Beaver Dam Eye Study found visual impairment worse than 20/40 vision in 5% of individuals(More)
This report may be used, in whole or in part, as the basis for development of clinical practice guidelines and other quality enhancement tools, or a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied. AHRQ is the lead Federal agency charged(More)
The goals of this systematic review and meta-analysis were to ascertain whether studies of nonsteroidal anti-inflammatory drugs (NSAIDs) summarized in the FDA reviews are ultimately published, to compare the methodologic and population characteristics of studies summarized in the FDA reviews with those reported in peer reviewed literature, and to compare(More)
O steoporosis is a systemic skeletal disease characterized by low bone mass, microarchitectural deterioration of bone tissue, and a consequent increase in bone fragility and susceptibility to fracture (1). Approximately 10 million people in the United States, 80% of whom are women, have osteoporosis, and another 18 million (83% women) have low bone mass(More)
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