Catherine Grgicak

Learn More
There are three dominant contributing factors that distort short tandem repeat profile measurements, two of which, stutter and variations in the allelic peak heights, have been described extensively. Here we characterise the remaining component, baseline noise. A probabilistic characterisation of the non-allelic noise peaks is not only inherently useful for(More)
When collecting biological evidence from a crime scene, it is important to determine the most effective and robust collection method to ensure maximum DNA recovery. Some common biological collection methods include swabbing, cutting, scraping, and taping. Although these common techniques for biological collection have been a mainstay of forensic analysis,(More)
iv ACKNOWLEDGEMENTS First and foremost, I would like to thank Dr. Catherine Grgicak and Ms. Julie James, for their constant support and guidance through the research and the writing phase of this thesis. I would like to also thank Dr. Kevin Hallock for his suggestions and direction during the design of the dynamic systems model presented in this thesis.(More)
ACKNOWLEDGEMENTS I would like to thank Dr. Grgicak, Dr. Cotton, and Mary Reed for agreeing to be on my thesis committee and for helping me with my research. I would also like to thank my friends and family for supporting me throughout the course of my research and I would especially like to thank my Fiancé for being there for all of my struggles and my(More)
—For forensic purposes, short tandem repeat allele signals are used as DNA fingerprints. The interpretation of signals measured from samples has traditionally been conducted by applying thresholding. More quantitative approaches have recently been developed, but not for the purposes of identifying an appropriate signal model. By analyzing data from 643(More)
The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Abstract—For forensic purposes, short tandem repeat allele signals are used as DNA fingerprints. The interpretation of signals measured from samples has traditionally been conducted by applying thresholding. More quantitative approaches(More)
  • Candace Renee Churinsky, Catherine Grgicak, Javier Giorgi, Renee Candace, Churinsky
  • 2013
Quantitative polymerase chain reaction (qPCR) techniques are currently used to quantify samples containing deoxyribonucleic acid (DNA) in forensic analyses. This technology can provide valuable information to an analyst regarding the amount of DNA present but lacks the ability to determine the quality of the sample. Electrochemistry-based biosensors that(More)
  • Lena Elizabeth Gunn, Catherine Grgicak, Assistant, Amy N Brodeur, M F S Instructor, Jessica Shea +2 others
  • 2013
iv ACKNOWLEDGEMENTS The invaluable services and tireless support of several individuals are gratefully acknowledged: First and foremost, I must thank my advisors Dr. Catherine Grgicak, Dr. Robin Cotton, and Amy Brodeur for their patience and guidance through the years. for always lending support when I struggled with this project and for providing great(More)
  • Gretchen Zaneta Johnson, Catherine Grgicak, Biomedical Forensic Instructor, Sciences, Amy Brodeur
  • 2012
iii ACKNOWLEDGEMENTS The invaluable services and tireless support of several individuals are gratefully acknowledged for their support and contributions: Dr. Catherine Grgicak, I am grateful for all of the guidance and support you have provided me with as a graduate student and for refining my laboratory skills throughout the entire process of this research(More)
  • 1