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Role of FRIGIDA and FLOWERING LOCUS C in Determining Variation in Flowering Time of Arabidopsis1[w]
TLDR
Analysis of Arabidopsis accessions revealed which accessions were likely to carry functional alleles, and it is estimated that approximately 70% of flowering time variation can be accounted for by allelic variation of FRI.
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Evolution of regulatory interactions controlling floral asymmetry
A key challenge in evolutionary biology is to understand how new morphologies can arise through changes in gene regulatory networks. For example, floral asymmetry is thought to have evolved many…
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Diversification and co-option of RAD-like genes in the evolution of floral asymmetry.
TLDR
The results suggest that duplication and divergence of RAD-like genes has involved a range of cis- and trans-regulatory changes, and it is possible that such changes led to the coupling of RAD to CYC regulation in the Antirrhinum lineage and hence the co-option of RAD had a role in the generation of flower dorsoventral asymmetry.
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Antagonistic activities of cotranscriptional regulators within an early developmental window set FLC expression level
TLDR
It is shown that antagonistic functions of the FLC activator FRIGIDA and the repressor FCA, at a specific stage of embryo development, determine FLC expression and flowering.
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Cancer genetics: Molecular signatures
TLDR
The authors argue that the propensity for a primary tumour to metastasise is linked to its genetic state as indicated by the geneexpression profile, which could be used to develop diagnostic tools that predict the clinical outcome of primary tumours on the basis of their geneexpression profiles at diagnosis.
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Genomics: Sea squirt genome released
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Cancer genetics: Making sense of missense
TLDR
Findings indicate that Artemis is also involved in the non-homologous end-joining phase of V(D)J recombination of Tand B-cell receptor genes, and T cells from these patients had a virtual absence of N nucleotide additions at the V( D)J junctions.
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Are you policy aware?
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Evolution: A tangled web
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Gene regulation: Join the club
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