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Protein kinase C (PKC) is a family of ten isozymes that play distinct and in some cases opposing roles in cell growth and survival. We recently reported that diamide, a diazene carbonyl derivative… (More)
Progression of human prostate cancer to a malignancy that is refractory to androgen-ablation therapy renders the disease resistant to available treatment options and accounts for the high prostate… (More)
Abstract Protein kinase C-α (PKC-α) activation is an important contributing factor in human breast cancer MCF-7 MDR cell drug resistance. We recently reported the use of N-myristoylated PKC-α… (More)
Protein kinase C (PKC) is a Ca2+- and phosphatidylserine (PS)-dependent protein kinase that is activated by unsaturated sn-1,2-diacylglycerol (DAG) in vivo. In addition to PS, unsaturated fatty acids… (More)
Racial/ethnic minorities are underrepresented in clinical research in the USA for multifarious reasons, including barriers to effective communication between researchers and potential research… (More)