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The YEASTRACT (http://www.yeastract.com) information system is a tool for the analysis and prediction of transcription regulatory associations in Saccharomyces cerevisiae. Last updated in June 2013, this database contains over 200,000 regulatory associations between transcription factors (TFs) and target genes, including 326 DNA binding sites for 113 TFs.(More)
Several years ago software development has become critical to the global market. In the past decade, as a reflection of globalization, software companies began to distribute their development processes in different places, creating distributed software development (DSD). With the growing of Distributed Software Development, organizations have attempt to(More)
Opportunistic Candida species often have to cope with inhibitory concentrations of acetic acid, in the acidic environment of the vaginal mucosa. Given that the ability of these yeast species to tolerate stress induced by weak acids and antifungal drugs appears to be a key factor in their persistence and virulence, it is crucial to understand the underlying(More)
Infections caused by opportunistic fungal pathogens have reached concerning numbers due to the increase of the immunocrompromised human population and to the development of antifungal resistance. This resistance is often attributed to the action of multidrug efflux pumps, belonging to the ATP-binding cassette (ABC) superfamily and the major facilitator(More)
<b>Background:</b> Along the last decade, there has been a significant increase in the adoption of the approaches based on Distributed Software Development (DSD). This approach has brought several competitive advantages, as well as new challenges such as communication and information sharing. In this context, the ontologies can provide benefits such as the(More)
Atrazine (ATZ) and S-metolachlor (S-MET) are two herbicides widely used, often as mixtures. The present work examined whether the presence of S-MET affects the ATZ-biodegradation activity of the bioaugmentation bacterium Pseudomonas sp. strain ADP in a crop soil. S-MET concentrations were selected for their relevance in worst-case scenarios of soil(More)