Cassandre Kinnaer

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Macrophages are motile leukocytes, targeted by HIV-1, thought to play a critical role in host dissemination of the virus. However, whether infection impacts their migration capacity remains unknown. We show that 2-dimensional migration and the 3-dimensional (3D) amoeboid migration mode of HIV-1-infected human monocyte-derived macrophages were inhibited,(More)
Results Here, we examined the migration ability of HIV-1infected primary human macrophages. We show that HIV-1 infection modifies dramatically the migration of macrophages in 3-dimentionnal (3D) environments. While the amoeboid migration mode is inhibited upon infection, another migration mode specifically used by macrophages in dense 3D environments, the(More)
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