Cassandra Falckenhayn

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In honey bees (Apis mellifera) the behaviorally and reproductively distinct queen and worker female castes derive from the same genome as a result of differential intake of royal jelly and are implemented in concert with DNA methylation. To determine if these very different diet-controlled phenotypes correlate with unique brain methylomes, we conducted a(More)
We generated RNA-seq data to assemble the transcriptome of the noble crayfish (Astacus astacus) from four combined tissues (abdominal muscle, hepatopancreas, ovaries, green glands). A total of 194 million read pairs with a length of 100 bp were generated. The transcriptome was assembled de novo using Trinity software, producing 158,649 non-redundant(More)
DNA methylation is a widely conserved epigenetic modification. The analysis of genome-scale DNA methylation patterns in various organisms suggests that major features of animal methylomes are widely conserved. However, based on the variation of DNA methyltransferase genes in invertebrates, it has also been proposed that DNA methylation could provide a(More)
The parthenogenetic all-female marbled crayfish is a novel research model and potent invader of freshwater ecosystems. It is a triploid descendant of the sexually reproducing slough crayfish, Procambarus fallax, but its taxonomic status has remained unsettled. By cross-breeding experiments and parentage analysis we show here that marbled crayfish and P.(More)
Aedes aegypti mosquitoes are important vectors of viral diseases. Mosquito host factors play key roles in virus control and it has been suggested that dengue virus replication is regulated by Dnmt2-mediated DNA methylation. However, recent studies have shown that Dnmt2 is a tRNA methyltransferase and that Dnmt2-dependent methylomes lack defined DNA(More)
1 1 Characterization of genome methylation patterns 2 in the desert locust Schistocerca gregaria 3 4 5 Cassandra Falckenhayn, Bart Boerjan, Günter Raddatz, Marcus Frohme, Liliane 6 Schoofs, and Frank Lyko 7 8 9 Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, 10 Heidelberg, Germany; Molecular Biotechnology and Functional Genome(More)
The parthenogenetic all-female marbled crayfish is a novel research model and potent invader of freshwater ecosystems. It is a triploid descendant of the sexually reproducing slough crayfish, Procambarus fallax, but its taxonomic status has remained unsettled. By cross-breeding experiments and parentage analysis we show here that marbled crayfish and P.(More)
6 1 Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), 7 Im Neuenheimer Feld 580, 69120 Heidelberg, Germany 8 2 Institute for Environmental Sciences, University of Koblenz-Landau, Forststrasse 7, 76829 9 Landau, Germany 10 3 Institute of Pharmacy and Biochemistry, Johannes Gutenberg-University Mainz, 11 Staudingerweg 5, 55128(More)
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