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A powerful way to discover key genes with causal roles in oncogenesis is to identify genomic regions that undergo frequent alteration in human cancers. Here we present high-resolution analyses of somatic copy-number alterations (SCNAs) from 3,131 cancer specimens, belonging largely to 26 histological types. We identify 158 regions of focal SCNA that are(More)
Citation Beroukhim, Rameen et al. " The Landscape of Somatic Copy-number Alteration Across Human Cancers. The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Users may view, print, copy, download and text and data-mine the content in such documents, for the purposes of academic research,(More)
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