Carsten Stüer

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BACKGROUND Most pilocytic astrocytomas (piloA) are benign growths (World Health Organization [WHO] grade 1) of the deep midline structures, the brainstem, and the cerebellum. To the authors' knowledge, the literature contains only scarce data regarding piloA in adults. METHODS Between 1995 and 2005, 44 patients (26 women and 18 men) underwent surgery for(More)
Alzheimer's disease (AD) is a neurodegenerative disorder primarily affecting regions of the brain responsible for higher cognitive functions. Immunization against β-amyloid (Aβ) in animal models of AD has been shown to be effective on the molecular level but also on the behavioral level. Recently, we reported naturally occurring autoantibodies against Aβ(More)
Saccular intracranial aneurysms are balloon-like dilations of the intracranial arterial wall; their hemorrhage commonly results in severe neurologic impairment and death. We report a second genome-wide association study with discovery and replication cohorts from Europe and Japan comprising 5,891 cases and 14,181 controls with approximately 832,000(More)
STUDY DESIGN Single-center prospective randomized controlled study. OBJECTIVE To evaluate the accuracy of robot-assisted (RO) implantation of lumbar/sacral pedicle screws in comparison with the freehand (FH) conventional technique. SUMMARY OF BACKGROUND DATA SpineAssist is a miniature robot for the implantation of thoracic, lumbar, and sacral pedicle(More)
STUDY DESIGN Retrospective, multicenter study of robotically-guided spinal implant insertions. Clinical acceptance of the implants was assessed by intraoperative radiograph, and when available, postoperative computed tomography (CT) scans were used to determine placement accuracy. OBJECTIVE To verify the clinical acceptance and accuracy of(More)
OBJECTIVE This study assessed the feasibility and safety of percutaneous posterior pedicle screw fixation for instabilities of the thoracic and lumbar spine, using standard instruments designed for the open approach and fluoroscopy. METHODS All patients who underwent percutaneous posterior pedicle screw fixation of the thoracic and lumbar spine were(More)
Lumbar spinal stenosis is a degenerative disease of the elderly population. Although microsurgical decompression has shown good long-term results, percutaneous techniques could provide an alternative in the presence of significant comorbidities. Eighty-seven interspinous process decompression devices (In-space; Synthes, Umkirch, Germany) were implanted(More)
The objective of the study was to generate prospective data to assess the clinical results after dynamic stabilization with the Cosmic® system (Ulrich Medical). Between April 2006 and December 2007, 103 consecutive patients were treated with Cosmic® for painful degenerative segmental instability ± spinal stenosis. The preoperative workup included(More)
Macrophage migration inhibitory factor (MIF) is a protein that is overexpressed in many tumors, such as colon and prostate cancer, melanoma, and glioblastoma multiforme (GBM). In its function as a cytokine, MIF induces angiogenesis, promotes cell cycle progression, and inhibits apoptosis. Recently, the molecular signal transduction has been specified: MIF(More)
Growth patterns of skull base chordomas are related to important neurovascular structures. Local invasiveness results in "clinically malignant" behavior. A high rate of transient neurological deficits occurs following radical surgery. At our institution, the principle of radical removal is not followed at any price. This study compared the results of our(More)