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Hormone receptor (HR) status has become an established target in treatment strategies of breast cancer. Population-based estimates of contralateral breast cancer (CBC) incidence by HR subtype in particular are limited. The aim of this study was to provide detailed data on CBC incidence for Germany. Invasive breast cancer data were extracted on 49,804 women(More)
BACKGROUND Exposure to radiation resulting from diagnostic imaging procedures probably increases late cancer risk. Patterns of care regarding the application of computed tomography (CT) imaging in testicular cancer patients were investigated. METHODS The database of a large German health insurance company comprising 850,000 insured men was searched for(More)
OBJECTIVES Several countries reported a drop in prescription of hormone replacement therapy (HRT) in the 2000s, followed by decreases in breast cancer incidence among postmenopausal women aged 50-69 years. The aim of this study was to provide hormone receptor specific incidence rates of breast cancer in Germany. METHODS Breast cancer data were extracted(More)
Comparisons of incidence estimates of testicular cancer subtypes beyond seminoma and non-seminoma are virtually missing in the epidemiologic literature. We analysed incidence data from population-based German cancer registries to provide subtype-specific incidences of testicular cancer. We pooled data from nine cancer registries from 1998 to 2003. We(More)
Germ cell tumours (GCTs) most often arise in the gonads, but some develop extragonadally. The aim of this study was to examine gender- and race-specific trends in incidence and survival of gonadal (GGCTs) and extragonadal GCTs (EGCTs) in the US from 1973 to 2007. We also examined the topographical distribution of EGCTs by race and gender. We estimated(More)
An increasing number of heroin addicts—especially young and first-time users—prefer inhaling the drug to intravenous injection. A rare complication of inhaling heroin is the development of a spongiform leukoencephalopathy (HSLE). Pathological background, symptoms, imaging, and therapeutical options are discussed on the basis of an example case.(More)
Vor dem Hintergrund der seit Einführung der diagnosebezogenen Fallpauschalen in einigen Bereichen gestiegenen Operationszahlen hat die große Zahl von Schilddrüsenoperationen wegen benigner Strumae in Deutschland eine kritische Diskussion über die Indikationsstellung zur Operation und die Qualität der Schilddrüsenchirurgie ausgelöst. Zur quantitativen(More)
Testicular cancer survival rates improved dramatically after cisplatin-based therapy was introduced in the 1970s. However, chemotherapy and radiation therapy are potentially carcinogenic. The purpose of this study was to estimate the risk of developing second primary cancers including the risk associated with primary histologic type (seminoma and(More)
BACKGROUND Malignant gonadal (GGCT) and extragonal germ cell tumors [GCT (EGCT)] are thought to originate from primordial germ cells. In contrast to well reported population-based data of GGCTs in males, analyses of GGCTs in females and EGCTs in both sexes remain limited. METHODS In a pooling project of nine population-based cancer registries in Germany(More)