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OBJECTIVE Growing evidence suggests that vascular risk factors (VRF) contribute to cognitive decline. The aim of this study was to investigate the impact of VRF on the conversion from mild cognitive impairment (MCI) to Alzheimer disease (AD) dementia. METHODS A total of 837 subjects with MCI were enrolled at baseline and followed up annually for 5 years.(More)
Microcapsules in the micrometer size range with walls of nanometer thickness are of both scientific and technological interest, since they can be employed as micro- and nano-containers. Liposomes represent one example, yet their general use is hampered due to limited stability and a low permeability for polar molecules. Microcapsules formed from(More)
OBJECTIVE To compare placebo responses in neuropathic pain syndromes. DESIGN Systematic literature review and meta-analysis. SETTING AND PATIENTS Randomized placebo-controlled trials assessing pain intensity or pain relief in any neuropathic pain syndrome published since 1995 with ≥5days follow-up. INTERVENTIONS Placebo response. OUTCOME MEASURES(More)
Polyamidoamine (PAMAM) dendrimers and their charged state in deuterium oxide have been investigated with proton pulsed field gradient diffusion nuclear magnetic resonance (PFG-NMR) and small-angle neutron scattering (SANS) techniques. NMR measurements suggest that significant variation of the hydrodynamic radius, calculated by the Stokes-Einstein relation(More)
We present a general description of the relationship between Fickian diffusivities at the continuum and molecular levels of description. Specifically, we address the issue of using molecular-level simulation techniques to generate Fickian diffusivities that can be rigorously used in the macroscopic evolution equations. Notably, we clarify the traditional(More)
A portable hydro-thermo-mechanical loading cell has been designed to enable in situ small angle neutron scattering (SANS) studies of proton exchange membranes (PEMs) under immersed tensile loadings at different temperatures. The cell consists of three main parts as follows: a letter-paper-size motor-driven mechanical load frame, a SANS friendly reservoir(More)
  • C Y Gao
  • 1992
From Nov. 1978 to Dec. 1988, autotransfusion was done in 25 patients, of which 23 suffered from traumatic hemothorax and 2 from spontaneous hemothorax. The amount of blood autotransfused was 500-2300ml (average 950ml). The time elapsed from accident was 5-44 hours (average 21 hours). Two patients had febrile reaction for a short period of time after(More)
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