Carolyn Womac

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Specific activities of the astroglial marker glutamine synthetase (GS), and the oligodendroglial marker glycerol-3-phosphate dehydrogenase (GPDH) were measured in the spinal cord of fetal guinea pigs and their dams following chronic exposure to low levels of lead (Pb) during gestation. In addition, the effects of Pb on intracellular trace metals (Cu, Fe,(More)
Rats were maintained on an ad lib diet containing 100 ppm cadmium (Group Cadmium-Diet) or a control diet with no added cadmium (Group Control-Diet). After 55 days of exposure to their respective diets, animals were tested for fluid intake using a nonchoice procedure that presented a 15% ethanol solution in the home cage for 5 days. Subsequently, all animals(More)
Twenty 2- to 3-week-old calves were fed a milk diet or a mixture of grain and hay. After acclimatization, all calves were dosed po with lead acetate for 7 days, either in solution via a nursing bottle or in a gelatin capsule. At the end of the treatment period, 6 of 10 calves fed milk were either dead or showed multiple signs of Pb poisoning. All calves fed(More)
Astroglia take up lead (Pb)in vivo andin vitro. In view of the fact that zinc affects both tissue deposition of Pb and clinical signs of Pb intoxication, the present study was carried out to test the effects of various Zn levels on lead toxicity in astroglia. Primary cultures of astroglia from 1- to 3-day-old neonatal rats were divided into three groups and(More)
Four different age groups of cattle, which had never been exposed to Pb, were used to determine normal age-related values for erythrocyte delta-aminolevulinic acid dehydratase (ALAD) activity. Acute or chronic Pb intoxication was experimentally induced in young calves, and their ALAD values were compared with the normal values. Results indicated that ALAD(More)
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