Carolyn Weinbaum

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BACKGROUND Nitrogen-containing bisphosphonates (N-BPs) have been designed to inhibit osteoclast-mediated bone resorption. However, it is now accepted that part of their anti-tumor activities is related to interference with the mevalonate pathway. METHODS We investigated the effects of zoledronic acid (ZOL), on cell proliferation and protein isoprenylation(More)
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