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OBJECTIVE A consistent pathologic feature seen in lungs of patients with pulmonary hypertension from thromboembolic disease is hyperplasia of the media of pulmonary arterioles. The molecular factors responsible for these vessel wall changes are unknown. Angiopoietin-1 is a gene responsible for the formation of the media of blood vessels in utero. We(More)
BACKGROUND AND AIM Gastroduodenal disease is more common among adults and children with cagA+ Helicobacter pylori infection, but disease severity varies among those infected with cagA+ strains. We examined whether cagA in situ expression can predict disease manifestations among H pylori-infected children. PATIENTS AND METHODS Fifty-one children were(More)
INTRODUCTION Hypertensive disorders in pregnancy (HDP) are a common complication of pregnancy. It is widely believed that this is a more common complication of adolescent pregnancies. Adolescent pregnancies are generally primiparous and result in earlier delivery, and these factors put them at a greater risk of preeclampsia. However, the generally lower(More)
INTRODUCTION Snoring is a common symptom of sleep disordered breathing (SDB), a condition that is present in 4% of the general population. SDB is identified by snoring and repetitive cessation of breathing during sleep accompanied by repetitive hypoxia and has been found to be associated with hypertension, stroke and heart attack. There is not depth of(More)
INTRODUCTION Snoring is a common symptom of Sleep Disordered Breathing (SDB), a condition that is present in 4% of the general population. SDB is identified by snoring and repetitive cessation of breathing during sleep accompanied by repetitive hypoxia and has been found to be associated with hypertension, stroke and heart attack.The general risk factors(More)
Received: 10 April 2003 Accepted: 17 April 2003 Published online: 14 June 2003 Springer-Verlag 2003 Sir, The patient was a term infant male with an uncomplicated prenatal and neonatal course, who was admitted at 6 weeks of age for RSV bronchiolitis, requiring respiratory support and monitoring. Following discharge, pediatric pulmonary evaluation was sought(More)
INTRODUCTION Preeclampsia is recognised as the leading cause of perinatal mortality and morbidity worldwide. Interest has been increasing recently as to the possible impact of sleep disordered breathing (SDB) on the mechanisms of preeclampsia, possibly by augmenting placental hypoxia during sleep. A biomarker of preeclampsia, sFlt-1, has also come to(More)
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