Carolyn P Evan

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BACKGROUND Chemokines and cytokines have been implicated in progression to castration-resistant prostate cancer (CRPC). METHODS Retrospective data were accessed from 122 men with serum samples(More)
BACKGROUND Insulin-like growth factor (IGF) and adipokines have been implicated in prostate cancer carcinogenesis. METHOD Data from 122 men with serum samples drawn within 3 months of starting ADT(More)
13 Background: Inflammation associated chemokines and cytokines have been shown in preclinical models to lead to the induction of castration resistance. We assessed whether higher blood cytokines and(More)
191 Background: IGF-1 has been shown to promote cancer growth by activation of PI3 kinase and downregulation of AMPK. IGFBP-1 shuttles IGF-1 across blood vessel membranes. Elevated IGFBP-1 blood(More)