Carolyn M. Price

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Although telomeres are not recognized as double-strand breaks (DSBs), some DSB repair proteins are present at telomeres and are required for telomere maintenance. To learn more about the telomeric function of proteins from the homologous recombination (HR) and non-homologous end joining pathways (NHEJ), we have screened a panel of chicken DT40 knockout cell(More)
We have identified two new telomere proteins, Tpt1 and Pat1, from the ciliate Tetrahymena thermophila. Although Tetrahymena telomerase is well characterized, only one telomere protein had previously been identified. This was the G-overhang binding-protein Pot1a. Tpt1 and Pat1 were isolated as Pot1a binding partners and shown to localize to telomeres. As(More)
Replicating the end of a linear chromosome poses a problem that can be solved by the combined action of the general DNA replication machinery, DNA repair factors, telomere proteins and telomerase. In this issue of The EMBO Journal, a new study by Moser et al examines the timing of replication, repair and telomere factor association with fission yeast(More)
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