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- Brian J. Lopresti, William E. Klunk, +8 authors Julie C. Price
- Journal of nuclear medicine : official…
- 2005
UNLABELLED
PET studies have been performed using the amyloid binding radiotracer Pittsburgh Compound B (PIB). Previous quantitative analyses using arterial blood showed that the Logan graphical… (More)
- Meryl A. Butters, Ellen M. Whyte, +9 authors James T. Becker
- Archives of general psychiatry
- 2004
CONTEXT
Cognitive impairment in late-life depression (LLD) is highly prevalent, disabling, poorly understood, and likely related to long-term outcome.
OBJECTIVES
To determine the characteristics… (More)
- Julie C. Price, William E. Klunk, +7 authors Chester A. Mathis
- Journal of cerebral blood flow and metabolism…
- 2005
A valid quantitative imaging method for the measurement of amyloid deposition in humans could improve Alzheimer's disease (AD) diagnosis and antiamyloid therapy assessment. Our group developed… (More)
- Carolyn C. Meltzer, Jeffrey P. Leal, Helen S. Mayberg, Henry N. Wagner, James Frost
- Journal of computer assisted tomography
- 1990
Due to the limited spatial resolution of positron emission tomography (PET), the accuracy of quantitative measurements of regional metabolism or neuroreceptor concentration is influenced by partial… (More)
- Walter H. Kaye, Guido K. W. Frank, +5 authors Leanne Rhodes
- The American journal of psychiatry
- 2001
OBJECTIVE
The authors' goal was to confirm that brain serotonin (5-HT) alterations are present in patients who have recovered from bulimia nervosa. Positron emission tomography imaging with… (More)
- Guido K. W. Frank, Ursula Franziska Bailer, +10 authors Walter H. Kaye
- Biological psychiatry
- 2005
BACKGROUND
Several lines of evidence support the possibility that disturbances of dopamine (DA) function could contribute to alterations of weight, feeding, motor activity, and reward in anorexia… (More)
- Paul H Soloff, Carolyn C. Meltzer, Carl B Becker, Phil J. Greer, Denny G. Constantine
- Psychiatry Research: Neuroimaging
- 2003
Prefrontal hypoperfusion and decreased glucose uptake in the prefrontal cortex (PFC) are found in violent criminal offenders, murderers and aggressive psychiatric patients. These abnormalities may be… (More)
- Martin A. Conway, David J. Turk, +4 authors James T. Becker
- Memory
- 1999
Memory for the experiences of one's life, autobiographical memory (AM), is one of the most human types of memory, yet comparatively little is known of its neurobiology. A positron emission tomography… (More)
- Angela R Wagner, Phil J Greer, +8 authors Walter H. Kaye
- Biological Psychiatry
- 2006
BACKGROUND
Individuals who are ill with anorexia (AN) and bulimia nervosa (BN) often have increased cerebrospinal fluid (CSF) volumes and decreased total gray and white matter volumes. It is unclear… (More)
- Owen T. Carmichael, Howard Aizenstein, +4 authors Yanxi Liu
- NeuroImage
- 2005
This study assesses the performance of public-domain automated methodologies for MRI-based segmentation of the hippocampus in elderly subjects with Alzheimer's disease (AD) and mild cognitive… (More)