Caroline Owens

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1. The contribution of activity in spinothalamic tract (STT) neurons to the pain and neurogenic hyperalgesia produced by an intradermal injection of 100 micrograms of capsaicin was investigated. Electrophysiological responses of identified STT neurons recorded in anesthetized monkeys were compared with psychophysical measurements of pain and hyperalgesia(More)
While acute splenic sequestration and splenic infarction are commonly observed in infants and young children with sickle cell anemia, they are rarely experienced by adult hemoglobin S homozygotes because the recurrent splenic infarction that takes place during childhood is typically followed by scarring, atrophy, and splenic fibrosis. Both acute splenic(More)
1. The responses of a population of 318 spinothalamic tract (STT) cells to mechanical stimulation of the skin were recorded in anesthetized macaque monkeys by several teams of investigators. The responses were subjected to k-means cluster analysis, a multivariate statistical procedure. 2. For an analysis that pertained to the responsiveness of the neurons,(More)
A collaborative study compared methods for measuring glycosylated haemoglobin in seven laboratories in the United Kingdom. No satisfactory standard for general use was found. Satisfactory internal quality control systems were in use for each assay which allowed the maintenance of a normal range in each participating laboratory. No satisfactory quality(More)
The aims of this study were to examine the pattern and relative utilization of exogenously supplied substrates by the perinatal rat lung and to study their functional relationship at a key period of lung maturation (3 days before birth until one day after birth). Maximal incorporation of 14C-labeled substrates (glucose, lactate, glycerol, and(More)
The responses of 8 wide-dynamic-range (WDR) STT neurons to electrical stimulation of the sensorimotor cortex or the cerebral peduncle were recorded intracellularly in anesthetized monkeys. EPSPs and spikes were evoked in STT neurons with short latencies ranging from 0.4 to 5.3 msec after the corticospinal volley, indicating a monosynaptic connection in at(More)
1. Recordings were made from the lumbosacral spinal cord in anesthetized macaque monkeys. The inhibitory effects of electrical stimulation of the periaqueductal gray (PAG) and the cerebral cortex or cerebral peduncle (CP) were tested and compared by recording 1) cord dorsum potentials evoked by stimulation of the sural nerve, 2) discharges recorded(More)
1. Intracellular recordings were made from 43 spinothalamic (STT) neurons in the lumbosacral region of the spinal cord in anesthetized macaque monkeys. The antidromic responses of these neurons to electrical stimulation of the ventral posterior lateral (VPL) nucleus of the thalamus were examined, and orthodromic responses to electrical stimulation of the(More)
1. Ballinger WF, Lacy PF (1972) Transplantation of intact pancreatic islets in rats. Surgery 72:175-186 2. Lacy PE, Kistianovsky M (1967) A method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 16: 35 3. LindaU AW, Steffes MW, Sorenson R (1969) Immunoassayable insulin content of subcellular fractions of rat islets.(More)
in the long-term control of glucose homeostasis. Effects on insulin secretion. Diabetologia 19:475-481 2. Kalkhoff RK (1975) Effects of oral contraceptive agents on carbohydrate metabolism. J Steroid Biochem 6:949-956 3. Houssay BA (1951) Action of sex hormones on experimental diabetes. Br Med J II: 505-510 4. Ionescu-Tirgoviste C, Pop E, Burdescu N, Bolcas(More)
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