Caroline Génébès

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BACKGROUND Chronic immunosuppression after solid-organ transplantation is associated with increased risk of developing malignancies. The purpose of this study was to determine the clinical characteristics and the outcome of thoracic malignancies in patients who have undergone solid-organ transplantation. METHODS Among a cohort of 2831 patients who(More)
OBJECTIVE To evaluate clinical outcome after accelerated partial breast irradiation (APBI) in the elderly after high-dose-rate interstitial multi-catheter brachytherapy (HIBT). METHODS AND MATERIALS Between 2005 and 2013, 70 patients underwent APBI using HIBT. Catheter implant was performed intra or post-operatively (referred patients) after lumpectomy(More)
10079 Background: Data regarding the management of patients with metastatic EHE are almost nonexistent. METHODS From 1990 to 2010, 78 adult patients (pts) with a confirmed diagnosis of EHE were referred to one of the 9 participating institutions, and their medical records reviewed. RESULTS Forty-two (54%) patients had metastatic disease. Median age was(More)
PURPOSE To review the clinical outcome of I-125 permanent prostate brachytherapy (PPB) for low-risk and intermediate-risk prostate cancer and to compare 2 techniques of loose-seed implantation. METHODS AND MATERIALS 574 consecutive patients underwent I-125 PPB for low-risk and intermediate-risk prostate cancer between 2000 and 2008. Two successive(More)
BACKGROUND Mutations of the proto-oncogene BRAF have been described in many cancers. Mutated BRAF causes overactive downstream signaling via MEK and ERK leading to excessive cell proliferation and survival. Their identification is of real interest because specific inhibitors have been developed. METHODS AND RESULTS We report the case of a patient with an(More)
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