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  • Marit Westerterp, Caroline C van der Hoogt, +5 authors Patrick C. N. Rensen
  • Medicine, Biology
  • Arteriosclerosis, thrombosis, and vascular…
  • 2006 (First Publication: 1 November 2006)
  • Objective—The role of cholesteryl ester transfer protein (CETP) in the development of atherosclerosis is still undergoing debate. Therefore, we evaluated the effect of human CETP expression onExpand
  • Jimmy F P Berbée, Caroline C van der Hoogt, D. Sundararaman, Louis M. Havekes, Patrick C. N. Rensen
  • Biology, Medicine
  • Journal of Lipid Research
  • 2005 (First Publication: 1 February 2005)
  • Studies in humans and mice have shown that increased expression of apolipoprotein C-I (apoC-I) results in combined hyperlipidemia with a more pronounced effect on triglycerides (TGs) compared withExpand
  • Jimmy F P Berbée, Caroline C van der Hoogt, +6 authors Patrick C. N. Rensen
  • Medicine, Biology
  • FASEB journal : official publication of the…
  • 2006 (First Publication: 1 October 2006)
  • Gram-negative sepsis is a major death cause in intensive care units. Accumulating evidence indicates the protective role of plasma lipoproteins such as high-density lipoprotein (HDL) in sepsis. ItExpand
  • Willeke de Haan, Jitske de Vries-van der Weij, +8 authors Patrick C. N. Rensen
  • Medicine
  • Circulation
  • 2008 (First Publication: 5 May 2008)
  • Background— Although cholesteryl ester transfer protein (CETP) inhibition is regarded as a promising strategy to reduce atherosclerosis by increasing high-density lipoprotein cholesterol, the CETPExpand
  • Caroline C van der Hoogt, Jimmy F. P. Berbée, +6 authors Patrick C. N. Rensen
  • Biology, Medicine
  • Biochimica et biophysica acta
  • 2006 (First Publication: 1 February 2006)
  • We have recently shown that the predominant hypertriglyceridemia in human apolipoprotein C1 (APOC1) transgenic mice is mainly explained by apoCI-mediated inhibition of the lipoprotein lipaseExpand
  • Gery Gerritsen, Caroline C van der Hoogt, +7 authors Ko Willems van Dijk
  • Biology, Medicine
  • Journal of Lipid Research
  • 2008 (First Publication: 1 May 2008)
  • Apolipoprotein E2 (apoE2)-associated hyperlipidemia is characterized by a disturbed clearance of apoE2-enriched VLDL remnants. Because excess apoE2 inhibits LPL-mediated triglyceride (TG) hydrolysisExpand
  • Caroline C van der Hoogt, Willeke de Haan, +7 authors Patrick C. N. Rensen
  • Biology, Medicine
  • Journal of Lipid Research
  • 2007 (First Publication: 1 August 2007)
  • In addition to efficiently decreasing VLDL-triglycerides (TGs), fenofibrate increases HDL-cholesterol levels in humans. We investigated whether the fenofibrate-induced increase in HDL-cholesterol isExpand
  • Sabine M Post, Martine Groenendijk, +6 authors Patrick C. N. Rensen
  • Biology, Medicine
  • Arteriosclerosis, thrombosis, and vascular…
  • 2006 (First Publication: 1 December 2006)
  • Objective—High-density lipoprotein (HDL) plays a key role in protection against development of atherosclerosis by reducing inflammation, protecting against LDL oxidation, and promoting reverseExpand