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Recent studies show that principal component analysis (PCA) of heartbeats is a well-performing method to derive a respiratory signal from ECGs. In this study, an improved ECG-derived respiration (EDR) algorithm based on kernel PCA (kPCA) is presented. KPCA can be seen as a generalization of PCA where nonlinearities in the data are taken into account by(More)
Epilepsy strongly affects the autonomic nervous system. Control mechanisms such as the one regulating the heart rate can be deeply affected during epileptic seizures. This effect of epilepsy can be measured in the ECG signal. In this paper, ECG segments of 35 children suffering from refractory epilepsy are studied. The goal is to determine whether(More)
Early detection of seizures could reduce associated morbidity and mortality and improve the quality of life of patients with epilepsy. In this study, the aim was to investigate whether ictal tachycardia is present in focal and generalized epileptic seizures in children. We sought to predict in which type of seizures tachycardia can be identified before(More)
In this paper a methodology to identify sleep apnea events is presented. It uses four easily computable features, three generally known ones and a newly proposed feature. Of the three well known parameters, two are computed from the RR interval time series and the other one from the approximate respiratory signal derived from the ECG using principal(More)
It is well known that epilepsy has a profound effect on the autonomic nervous system, especially on the autonomic control of heart rate and respiration. This effect has been widely studied during seizure activity, but less attention has been given to interictal (i.e. seizure-free) activity. The studies that have been done on this topic, showed that heart(More)
BACKGROUND Autonomic dysfunctions occur during but also in between seizures. During seizures, the direct involvement of central autonomic control centers cause specific changes in heart rate and respiration. The pathophysiology of autonomic dysfunctions that are observed in the interictal period is more difficult to explain. These alterations are most(More)
GOAL This paper presents a methodology for the automatic detection of sleep apnea from single-lead ECG. METHODS It uses two novel features derived from the ECG, and two well-known features in heart rate variability analysis, namely the standard deviation and the serial correlation coefficients of the RR interval time series. The first novel feature uses(More)
Epileptic seizures are typically related to autonomic dysfunction. During seizures, the cardiac and respiratory mechanisms are deeply affected. This effect of epilepsy can also occur a few seconds before the seizure onset in the EEG. In addition, the interaction between respiration and heart rate is also expected to be affected. This study aims to determine(More)
The tachogram is typically constructed by detecting the R peaks in the electrocardiogram (ECG). Sometimes the ECG is however very noisy, which makes it hard to find the R peaks in these cases by using only the ECG. Information from other signals can then be used in order to find the R peaks. In this paper, a method is suggested that is able to automatically(More)
Respiration is one of the main modulators causing heart rate variability (HRV). However, when interpreting studies of HRV, the effect of respiration is largely ignored. We, therefore, previously proposed to take respiratory influences into account by separating the tachogram in a component that is related to respiration and one that contains all residual(More)