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It has been proposed that cell-free nucleic acids in the plasma participate in tumorigenesis and the development of metastases via transfection-like uptake of such nucleic acids by susceptible cells. This putative phenomenon is tentatively referred to as "genometastasis." In the present study, we examined the effects on cultured cells of plasma from healthy(More)
BACKGROUND Gonadoblastoma (GB) is regarded as an in situ form of germ cell tumor in dysgenetic gonads, and 30% of patients with GB develop a dysgerminoma/seminoma tumor. OBJECTIVE Determine whether OCT3/4 and β-catenin are expressed in dysgenetic gonads before GB development and whether TSPY participates in the OCT3/4-β-catenin pathways in the malignant(More)
Recently, there has been renewed interest in perceptive problems of dyslexics. A polemic research issue in this area has been the nature of the perception deficit. Another issue is the causal role of this deficit in dyslexia. Most studies have been carried out in adult and child literates; consequently, the observed deficits may be the result rather than(More)
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