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  • Carolina Aloisio, Anselmo Gomes de Oliveira, Marcela Raquel Longhi
  • Chemistry, Medicine
  • Drug development and industrial pharmacy
  • 2014 (First Publication: 1 July 2014)
  • Abstract In order to investigate the effect on the aqueous solubility and release rate of sulfamerazine (SMR) as model drug, inclusion complexes with β-cyclodextrin (βCD), methyl-β-cyclodextrinContinue Reading
  • Carolina Aloisio, Marcela Raquel Longhi, Anselmo Gomes de Oliveira
  • Chemistry, Medicine
  • Journal of pharmaceutical sciences
  • 2015 (First Publication: 1 October 2015)
  • The aim of this work was the development and characterization of a biocompatible microemulsion (ME) containing soybean oil (O), phosphatidylcholine/sodium oleate/Eumulgin®HRE40 as the surfactantContinue Reading
  • Carolina Aloisio, Anselmo Gomes de Oliveira, Marcela Raquel Longhi
  • Chemistry, Medicine
  • Journal of pharmaceutical and biomedical analysis
  • 2014 (First Publication: 1 November 2014)
  • This study investigated the effect on solubility and release of ternary complexes of sulfamerazine (SMR) with β-(βCD), methyl-(MβCD) and hydroxypropyl-β-cyclodextrin (HPβCD) using meglumine (MEG) asContinue Reading
  • Alicia Delrivo, Carolina Aloisio, Marcela Raquel Longhi, Gladys Ester Granero
  • Chemistry, Medicine
  • AAPS PharmSciTech
  • 2018 (First Publication: 15 February 2018)
  • We propose an in vitro permeability assay by using a modified lipid membrane to predict the in vivo intestinal passive permeability of drugs. Two conditions were tested, one with a gradient pH (pHContinue Reading
  • Claudia Garnero, Ana Karina Chattah, Carolina Aloisio, Luis M. Fabietti, Marcela Raquel Longhi
  • Chemistry, Medicine
  • AAPS PharmSciTech
  • 2018 (First Publication: 10 May 2018)
  • Norfloxacin, an antibiotic that exists in different solid forms, has very unfavorable properties in terms of solubility and stability. Binary complexes of norfloxacin, in the solid form C, andContinue Reading
  • Carolina Aloisio, Micaela Ponce-Ponte, Gladys Ester Granero, Marcela Raquel Longhi
  • Medicine, Chemistry
  • AAPS PharmSciTech
  • 2018 (First Publication: 19 June 2018)
  • The aim of this work was to predict the permeability of two model drugs, sulfamerazine (SMR) and indomethacin (INM), and to determine the effect on their apparent permeabilities by complexation withContinue Reading