Carole Else Eboumbou Moukoko

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Schistosome infection is a major public health concern affecting millions of people living in tropical regions of Africa, Asia, and South America. Schistosomes cause mild clinical symptoms in most subjects, whereas a small proportion of individuals presents severe clinical disease (as periportal fibrosis (PPF)) that may lead to death. Severe PPF results(More)
Hepatic periportal fibrosis (PPF), associated with portal hypertension, is a major pathological consequence of infections with Schistosoma mansoni and Schistosoma japonicum. Indeed, affected subjects may die from portal hypertension. Previous studies have indicated that tumor necrosis factor alpha (TNF-alpha) may aggravate fibrosis. We therefore(More)
In more than one way, the development of antiparasitic vaccines is challenging, but major efforts have been made. A large number of clinical trials have been carried out and a few antigens have been tested in the endemic zone, especially against malaria. So far, no vaccine candidate has shown a sufficient and long-lasting effectiveness that would be useful(More)
Background: In Cameroon, as in many malaria endemic countries in Africa, blood donors are not routinely screened for Plasmodium infection that potentially could lead to severe malaria in some recipients. This study aimed at defining the prevalence of malaria among blood donors in Cameroon, and determining the risk of transfusion-transmitted malaria (TTM)(More)
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