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  • Carola Huthmacher, Andreas Hoppe, Sascha Bulik, Hermann-Georg Holzhütter
  • Biology, Computer Science, Medicine
  • BMC Systems Biology
  • 2009 (First Published: 1 December 2010)
  • BackgroundDespite enormous efforts to combat malaria the disease still afflicts up to half a billion people each year of which more than one million die. Currently no approved vaccine is availableContinue Reading
  • Andreas Schlicker, Carola Huthmacher, Fidel Ramírez, Thomas Lengauer, Mario Albrecht
  • Biology, Computer Science, Medicine
  • German Conference on Bioinformatics
  • 2006 (First Published: 1 March 2007)
  • MOTIVATION Large amounts of protein and domain interaction data are being produced by experimental high-throughput techniques and computational approaches. To gain insight into the value of theContinue Reading
    Kinetic modelling of complex metabolic networks - a central goal of computational systems biology - is currently hampered by the lack of reliable rate equations for the majority of the underlyingContinue Reading
  • Carola Huthmacher, Christoph Gille, Hermann-Georg Holzhütter
  • Biology, Medicine
  • Journal of theoretical biology
  • 2008 (First Published: 1 June 2008)
  • Protein-protein interactions are operative at almost every level of cell structure and function as, for example, formation of sub-cellular organelles, packaging of chromatin, muscle contraction,Continue Reading
  • Carola Huthmacher, Christoph Gille, Hermann-Georg Holzhütter
  • Biology, Medicine
  • Genome informatics. International Conference on…
  • 2007 (First Published: 1 December 2007)
  • Protein-protein interactions are operative at almost every level of cell function. In the recent years high-throughput methods have been increasingly used to uncover protein-protein interactions atContinue Reading