American journal of respiratory and critical care…
2008
RATIONALE
In interstitial lung disease complicating systemic sclerosis (SSc-ILD), the optimal prognostic use of baseline pulmonary function tests (PFTs) and high-resolution computed tomography (HRCT)… (More)
American journal of respiratory and critical care…
2002
Fibrosing alveolitis associated with systemic sclerosis (FASSc) has a better prognosis than idiopathic pulmonary fibrosis. In view of recent reports that idiopathic nonspecific interstitial pneumonia… (More)
OBJECTIVE
The lack of randomized controlled trials (RCTs) in pulmonary fibrosis in systemic sclerosis (SSc) has hampered an evidence-based approach to treatment. This RCT was undertaken to… (More)
BACKGROUND
Scleroderma renal crisis (SRC) is an important complication of systemic sclerosis, causing acute renal failure, and usually hypertension.
AIMS
To review the clinical and pathological… (More)
In skin, the profibrotic protein connective tissue growth factor (CTGF) is not normally expressed. However, when skin cells are exposed to transforming growth factor-beta (TGF-beta), CTGF is induced… (More)
OBJECTIVE
To determine the prevalence of systemic sclerosis associated pulmonary arterial hypertension (SScPAH), evaluate outcome, and identify predictors of mortality in a large patient cohort.
… (More)
OBJECTIVE
This study assessed the validity of the Eating Disorder Examination--Questionnaire (EDE-Q) in identifying eating disorder symptoms in female substance abusers.
METHOD
Subjects were… (More)
OBJECTIVE
To develop and test a severity scale for individual organ involvements in systemic sclerosis (SSc, scleroderma).
METHODS
An international study group completed the following tasks: (1)… (More)
Connective tissue growth factor (CTGF) is overexpressed in a variety of fibrotic disorders, presumably secondary to the activation and production of transforming growth factor-beta (TGF-beta), a key… (More)