Carol M. Frattali

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Context exerts a powerful effect on cognitive performance and is clearly important for language processing, where lexical, sentential, and narrative contexts should differentially engage neural systems that support lexical, compositional, and discourse level semantics. Equally important, but thus far unexplored, is the role of context within narrative, as(More)
BACKGROUND fMRI language tasks readily identify frontal language areas; temporal activation has been less consistent. No studies have compared clinical visual judgment to quantitative region of interest (ROI) analysis. OBJECTIVE To identify temporal language areas in patients with partial epilepsy using a reading paradigm with clinical and ROI(More)
OBJECTIVE To investigate the degree of language dominance in patients with left and right hemisphere seizure foci compared to normal volunteers using a fMRI reading comprehension task. METHODS Fifty patients with complex partial epilepsy, aged 8 to 56 years and 33 normal volunteers, aged 7 to 34 had fMRI (1.5 T) and neuropsychological testing.(More)
BACKGROUND fMRI language tasks reliably identify language areas in presurgical epilepsy patients, but activation using single paradigms may disagree with the intracarotid amobarbital test (IAT). OBJECTIVE To determine whether a panel of fMRI tasks targeting different aspects of language processing increases accuracy in determining hemisphere language(More)
Prepared by: The Academy of Neurologic Communication Disorders and Sciences’ ad hoc Practice Guidelines Coordinating Committee, Lee Ann C. Golper (Chair), Robert T. Wertz, Carol M. Frattali, Kathryn Yorkston, Penelope Myers, Richard Katz, Pelagie Beeson, Mary R. T. Kennedy, Kathryn Bayles, and Julie Wambaugh (members) with co-sponsorship support form the(More)
OBJECTIVE To assess aggression and psychiatric comorbidity in a sample of children with hypothalamic hamartomas and gelastic seizures and to assess psychiatric diagnoses in siblings of study subjects. METHOD Children with a clinical history of gelastic seizures and hypothalamic hamartomas (n = 12; age range 3-14 years) had diagnoses confirmed by video-EEG(More)
OBJECTIVE To characterize the cognitive deficits in children with gelastic seizures and hypothalamic hamartoma and investigate the relationship of seizure severity to cognitive abilities. METHODS Eight children with gelastic seizures and hypothalamic hamartoma completed a neuropsychological battery of standardized and age-normed tests, including the(More)
PURPOSE Hypothalamic hamartomas (HHs) have been associated with uncontrolled seizures, and aggressive therapy including surgery is often recommended. However, some patients, particularly those with other findings associated with Pallister-Hall syndrome (PHS), have a more benign course. METHODS Thirty-seven of 40 PHS patients and 16 of 16 patients with(More)
To characterize the language deficits in corticobasal degeneration (CBD) and their relation to neuroradiologic findings, the authors administered a standardized battery of neurobehavioral tests and performed MRI studies on 15 patients with CBD. Eight patients (53%) had classifiable aphasias, including anomic, Broca's and transcortical motor aphasias. The(More)