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Observers, searching for targets among distractor items, guide attention with a mix of top-down information--based on observers' knowledge--and bottom-up information--stimulus-based and largely independent of that knowledge. There are 2 types of top-down guidance: explicit information (e.g., verbal description) and implicit priming by preceding targets(More)
Dopamine (DA) and serotonin (5HT) are reported to serve important roles in aggression in a wide variety of animals. Previous investigations of 5HT function in adult Drosophila behavior have relied on pharmacological manipulations, or on combinations of genetic tools that simultaneously target both DA and 5HT neurons. Here, we generated a transgenic line(More)
We undertook this project to integrate context sensitive computer-based educational and decision making aids into the film interpretation and reporting process, and to determine the clinical utility of this method as a guide for further system development. An image database of 347 digital mammography images was assembled and image features were coded. An(More)
Malignant gliomas are the most common tumors originating within the central nervous system and account for over 15,000 deaths annually in the United States. The median survival for glioblastoma, the most common and aggressive of these tumors, is only 14 months. Therapeutic strategies targeting glioma cells migrating away from the tumor core are currently(More)
On December 2, 2015, a terror attack in the city of San Bernardino, California killed 14 Americans and injured 22 in the deadliest attack on U.S. soil since September 11, 2001. Although emergency personnel and law enforcement officials frequently deal with multi-casualty incidents (MCIs), what occurred that day required an unprecedented response. Most of(More)
OBJECTIVE Endothelial dysfunction in childhood obesity may precede cerebrovascular damage and cognitive impairment in adulthood. A noninvasive proxy of microvascular health is required to identify the risk for microvascular damage in obese children. DESIGN AND METHODS The associations of hippocampal volumes and global cerebral atrophy were assessed with(More)
All of the key questions remain up-to-date. None of the investigators has any affiliations or financial involvement that conflicts with the material presented in this report. iii Acknowledgments The authors gratefully acknowledge the following individuals for their contributions to this project: