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A relationship between psychological factors and skin diseases has long been hypothesized. Psychodermatology addresses the interaction between the mind and the skin. Today, we know that it is essential to consider both biopsychosocial approaches and path physiological approaches to treatment, involving general practitioners, psychiatrists, dermatologists(More)
Background. Infection with and persistence of high-risk human papillomavirus (HR-HPV) are the strongest risk factors for cervical cancer. In addition, other genital microorganisms may also be involved in the progression of HPV-associated lesions. Objetive. To evaluate the association of the vaginal microbiota (Candida spp., Trichomonas vaginalis, and(More)
BACKGROUND Burning mouth syndrome (BMS) is a frequently occurring disease characterized by a burning or painful sensation in the tongue and/or other oral sites without clinical mucosal abnormalities or lesions. Its etiopathology is unknown, although local, systemic, and psychological factors have been associated with BMS. The syndrome is multifactorial, and(More)
Histoplasmosis is a systemic infection caused by the dimorphic fungus Histoplasma capsulatum. In immunocompromised patients, primary pulmonary infection can spread to the skin and meninges. Clinical manifestations appear in patients with a CD4(+) lymphocyte count of less than 150 cells/μL. Coccidioidomycosis is a systemic mycosis caused by Coccidioides(More)
BACKGROUND Interleukin (IL) 33 is a recently identified pleiotropic cytokine that influences the activity of multiple cell types and orchestrates complex innate and adaptive immune responses. METHODS We performed an extensive review of the literature published between 2005 and 2013 on IL-33 and related cytokines, their functions, and their regulation of(More)
BACKGROUND In recent years, research on psoriasis has focused on the identification of biomarkers for the diagnosis, pathogenesis, prognosis, or therapeutic response of the disease. These studies could provide insights into the susceptibility and natural history of psoriasis. The identification of biomarkers related to comorbidities in psoriasis, such as(More)
BACKGROUND Inflammation-driven immune dysfunction supports the development of several chronic human disorders including skin diseases. Nonantibiotic macrolides have anti-inflammatory and/or immunomodulatory activity that suggests the exploitation of these in the treatment of skin diseases characterized by inflammatory disorders. MATERIALS AND METHODS We(More)
Epidemiological relationships were established more than 100 years ago between precursory lesions of cervical cancer and risky sexual behaviour. For various decades medicine has, unsuccessfully, tried to find the relationships between the agents responsible for sexually transmitted infections with this neoplasia. Thus, epidemiological studies supported by(More)
The syndrome of chronic vulvar pain, which is traditionally referred to as vulvodynia, but is nowadays called either local or general vulvar dysesthesia, continues to be enigmatic for doctors involved in its diagnosis and treatment. Most patients suffering from local dysesthesia or vestibulitis have undergone multiple local or systemic treatments, generally(More)
In Northwestern Spain (NWS), the annual incidence of AIDS diagnoses increased from 1984 (when the first case was diagnosed) until 1996. However, since 1996, this incidence has reduced considerably, including a notable 40% reduction between 1997 and 1998. The Galician Register of AIDS supplies information on the evolution of AIDS pathology in NWS. This(More)