Carmen Michán

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Rob is regarded as a constitutively expressed protein, although little is known about how rob gene is regulated. We show here by reverse transcription-PCR that the transcriptional levels of rob are strongly down-regulated in response to the superoxide-generating agent paraquat (PQ). Repression reached a maximum of 20-fold after 10 min exposure at 10 microM(More)
At least twenty-seven proteins belong to the XylS/AraC family of prokaryote transcriptional regulators. All members of this family except CelD and TetD are positive transcriptional factors. Three subgroups were distinguished within the family in accordance with the Needleman and Wunsch algorithm. Multiple alignment of these proteins revealed that they(More)
The Escherichia coli melR gene encodes MelR protein which is a member of the AraC/XylS family of bacterial transcription activators. The function of MelR was investigated by making a targeted deletion in the melR gene of the Escherichia coli chromosome. MelR is a transcription activator essential for melibiose- dependent expression of the melAB operon which(More)
Evolution and adaptation are an important and basic part of biology and with the advancement of high-throughput technologies new approaches are available to exploit these properties for biotechnological applications. In this highlight we underscore a number of recent articles that we believe are highly relevant to biotechnology, including the discovery of(More)
In Meschke and Schrempf (2010), the authors present a very colourful research article on the potential of Strepto-myces lividans as a biocontrol agent. Streptomyces are well-characterized soil microorganisms that have attracted the attention of scientists because of their potential as producers of secondary metabolites that are of interest to the pharma(More)
At birth, the human colon is rapidly colonized by a vast amount of gut microbes that affect host physiology and metabolism because of their ability to ferment nutrients and secrete bioactive compounds (de Vos, 2013). Lately, different reports are exploring their potential use for the treatment of a wide variety of diseases, although the clinical use of the(More)
The removal of pollutants from the environment has been declared a priority by a number of Environmental Protection Agencies (Roze et al., 2009). A great number of aerobic pathways have been deciphered and their relevance in microbiology and biotechnology has been reviewed several times (Garmendia et al. In the area of biodegradation the role anaerobes and(More)
In this special issue a series of articles appear detailing methods of energy generation under different conditions; processes which are related to the future vision of microbes as a source of electric power (Lovley, 2009). Methanogenesis is identified as an important part of the biogeochemical carbon cycle in diverse anaerobic environments. Methane is an(More)