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Tea is the most consumed drink in the world after water. Green tea is a 'non-fermented' tea, and contains more catechins, than black tea or oolong tea. Catechins are in vitro and in vivo strong antioxidants. In addition, its content of certain minerals and vitamins increases the antioxidant potential of this type of tea. Since ancient times, green tea has(More)
The mechanisms that lead to loss of MHC class I expression in different types of tumors are not yet fully known. Accordingly, we studied colorectal carcinomas to elucidate the specific mechanisms of evasion of the T-cell immune response. We selected tumors with total loss of MHC class I expression and studied 124 colorectal carcinomas with(More)
We measured daily dietary Cr intake in southern Spain by sampling duplicate diets for seven consecutive days in different population groups. Cr was determined by electrothermal atomization-atomic absorption spectrometry. The samples were mineralized in a digestion block with HNO(3), HClO(4) and V(2)O(5). A total of 161 duplicate diets from twenty-three(More)
Concentrations of aluminium in drinking waters (tap water, still mineral water and sparkling mineral water), fruit juices and soft drinks were determined using graphite furnace atomic absorption spectrometry (GFAAS) of samples processed with a HNO3-V205 acid digestion pre-treatment. In water samples, aluminium was determined directly. We verified the(More)
An in vitro method was used to study the dialysable fraction of chromium (Cr) from the diet which simulates human gastric and intestinal digestion. The percentage of dialysed Cr was used to assess the bioavailability. The duplicate diet approach was used to obtain ten different sets of samples each representative of the normal diet consumed in southern(More)
An accurate and precise method is described for the direct determination of Cd in wine, beer and other alcoholic beverages by electrothermal atomization-atomic absorption spectrometry (ETA-AAS). The graphite furnace program was optimized and samples were pretreated with nitric acid and pentoxide vanadium in a digestion block at 120 degrees C for 90 min. The(More)
Potable water, fruit juices and soft drinks are some of the most widespread beverages in the habitual diet, and they can contribute to chromium dietary intake. We determined the concentration of chromium in 90 different samples of beverages widely consumed in Spain. Graphite furnace atomic absorption spectrometry was used to analyze samples processed with a(More)
hESCs (human embryonic stem cells) are pluripotent cells derived from the ICM (inner cell mass) of blastocysts that can be used to derive several kinds of cells of the human body for the treatment of some previously untreated diseases. In considering the future use of hESCs in regenerative medicine and cell-therapy programmes, several research centres have(More)
Human embryonic stem cells (hESCs) have an unlimited capacity to proliferate by a self-renewal process and can be differentiated in the three germ layers, opening doors to new clinical therapies to replace missing or damaged cells. The number of research groups and projects using human stem cells has increased largely in the last 5 yr. The creation of stem(More)
HLA class I loss or down-regulation is a widespread mechanism used by tumor cells to avoid tumor recognition by cytotoxic T lymphocytes, and thus favor tumor immune escape. Multiple mechanisms are responsible for these HLA class I alterations. In different epithelial tumors, loss of heterozygosity (LOH) at chromosome region 6p21.3, leading to HLA haplotype(More)