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OBJECTIVE Membrane transporters are proteins that play a crucial role in resistance to chemotherapy. The aim of this study was to assess the influence of membrane transporter protein expression on chemotherapeutic response. MATERIAL AND METHODS One hundred and forty seven samples of tumor tissue were collected from 143 patients; 35 samples were obtained(More)
BACKGROUND Facial lesions in frontal fibrosing alopecia (FFA) have been poorly described in published series. OBJECTIVE We sought to describe facial lesions in FFA. METHODS We reviewed our series of 55 cases of FFA, selecting 12 cases with clinically significant facial lesions. We performed a histologic study of these lesions. RESULTS In addition to(More)
We report two cases of acute hepatotoxicity after treatment with amoxicillin-clavulanic. Viral hepatitis serology and autoantibodies were negative. Biliary tree obstruction and other etiologies were excluded. After discontinuation of the drug the evolution was favorable with clinical improvement and normalization of liver tests. Liver biopsy made in one(More)
A case of Kaposi syndrome is described in a 28-year-old heterosexual male with acquired immunodeficiency syndrome. The disease began clinically with pulmonary disease, without mucocutaneous lesions. This form of presentation is extremely infrequent and has not been described in non-homosexual subjects. Clinical manifestations were fever, cough and dyspnea.(More)
The case of a patient with Ménétrier's disease in association with inactive ulcerative colitis of 7 years of evolution is presented. Diagnosis was confirmed by exploratory laparotomy and the symptoms of anemia and hypoproteinemia improved following treatment with octreotide. On review of the literature this was found to be the third case of Ménétrier's(More)
Cutaneous adverse effects of interferon are common, including particularly injection site reactions, alopecia, stomatitis, pruritus, and flare-ups of psoriasis, eczema, or lichen planus.1 Interferon-induced sarcoidosis is a lesser-known adverse effect that may affect 0.2% of patients.2 The first case of this condition was reported in 1987 in a patient(More)
Lymphangiosarcoma is an uncommon vascular tumor that usually develops in longstanding lymphedema. We gathered the cases of lymphangioma observed in a hospital and attempted to analyze their characteristics: age, sex, localization, treatment and follow-up data. We studied five cases: three cases of Stewart-Treves syndrome after mastectomy and radiotherapy(More)