Carmen Ballesteros-Merino

  • Citations Per Year
Learn More
Background Assessment of tumor-infiltrating immune cells using immunohistochemistry (IHC) has been shown to be a powerful way to predict patient prognosis, notably in colon cancer [1, 2]. Similar observations were made in patients with head and neck squamous cell carcinoma (HNSCC), where T cell infiltration is associated with prolonged survival [3,4]. More(More)
Background Bavituximab is a novel chimeric IgG1 monoclonal antibody targeting the membrane phospholipid, phosphatidylserine (PS), externalized on the luminal surface of endothelium in tumors, tumor cells, and tumor exosomes under stressor conditions in the tumor microenvironment. PS exposure on tumor vessels is increased by chemotherapy and irradiation,(More)
4501. Coinhibition & Costimulation O4 Computational identification, functional characterization, and antibody blockade of a new immune checkpoint in the TIGIT family of interacting molecules Ofer Levy, Christopher Chan, Gady Cojocaru, Spencer Liang, Eran Ophir, Sudipto Ganguly, Amir Toporik, Maya Kotturi, Tal Fridman Kfir, Benjamin M. Murter, Kathryn(More)
Evaluation of T lymphocyte frequency provides prognostic information for patients with oral squamous cell cancer (OSCC). However, the effect of simultaneously evaluating T cell frequency and assessing suppressive elements and defects in antigen-processing machinery (APM) has not been clarified. Simultaneous characterization of CD3+, CD8+, FoxP3+, CD163+,(More)
Lung cancer is currently the most common cause of cancer-related death in the world and approximately 85% of all lung cancers are non-small cell lung cancer (NSCLC). Previous studies have shown that patients with NSCLC containing high densities of CD8+ memory T cells have a survival advantage. Others have identified an association between relatively high(More)
  • 1