Carmelo Rodríguez

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The effect of high altitude on reducing birth weight is markedly less in populations of high- (e.g., Andeans) relative to low-altitude origin (e.g., Europeans). Uterine artery (UA) blood flow is greater during pregnancy in Andeans than Europeans at high altitude; however, it is not clear whether such blood flow differences play a causal role in(More)
Fetal growth is reduced at high altitude, but the decrease is less among long-resident populations. We hypothesized that greater maternal uteroplacental O(2) delivery would explain increased fetal growth in Andean natives versus European migrants to high altitude. O(2) delivery was measured with ultrasound, Doppler and haematological techniques.(More)
OBJECTIVE This prospective study was designed to determine whether variation in angiogenic (placental growth factor [PlGF]) and/or anti-angiogenic (soluble fms-like tyrosine kinase [sFlt-1]) factors contribute to the protective effect of highland ancestry (Andean) from altitude-associated reductions in fetal growth. STUDY DESIGN Plasma sFlt-1 and PlGF(More)
BACKGROUND Strong evidence supports the use of metered-dose inhalers combined with a spacer for delivering rapid-acting inhaled beta-2 agonists in the treatment of acute exacerbations of asthma in children. The high cost and lack of availability of commercially produced spacers however, have limited their use in developing countries. OBJECTIVES The aim of(More)
Received (received date) Revised (revised date) Naive Bayes models have been successfully used in classification problems where the class variable is discrete. These models have also been applied to regression or prediction problems, i.e. classification problems where the class variable is continuous, but usually under the assumption that the joint(More)
Factorisation of probability trees is a useful tool for inference in Bayesian networks. Prob-abilistic potentials some of whose parts are proportional can be decomposed as a product of smaller trees. Some algorithms, like lazy propagation, can take advantage of this fact. Also, the factorisation can be used as a tool for approximating inference, if the(More)
Oxidative stress has been implicated in the uteroplacental ischemia characteristic of preeclampsia and small-for-gestational-age (SGA) birth, both of which are more common at high (>2500 m) vs low altitude. Since Andeans are protected relative to Europeans from the altitude-associated rise in SGA, we asked whether alterations in maternal antioxidant status(More)
In this paper, we propose a methodology for relevance analysis of performance indicators in higher education based on the use of Bayesian networks. These graphical models provide, at first glance, a snapshot of the relevant relationships among the variables under consideration. We analyse the behaviour of the proposed methodology in a practical case,(More)