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We present in this paper an adaptive security model for Multi-agent systems. A security meta-model has been developed in which the traditional role concept has been extended. The new concept incorporates the need of both security management as used by role-based access control (RBAC) and agent functional behaviour in agent-oriented Software Engineering(More)
This paper focuses on the problem of representing, in a meaningful way, the knowledge involved in the HealthAgents project. Our work is motivated by the complexity of representing Electronic Health-care Records in a consistent manner. We present HADOM (HealthAgents Domain Ontology) which conceptualises the required HealthAgents information and propose(More)
A distributed decision support system involving multiple clinical centres is crucial to the diagnosis of rare diseases. Although sharing of valid diagnosed cases can facilitate later decision making, possibly from geographically different centres, the released information could reveal patient privacy if it is not properly protected. Clinical centres may(More)
Knowledge discovery on biomedical data can be based on on-line, data-stream analyses, or using retrospective, timestamped, off-line datasets. In both cases, changes in the processes that generate data or in their quality features through time may hinder either the knowledge discovery process or the generalization of past knowledge. These problems can be(More)
This study demonstrates that 3T SV-MRS data can be used with the currently available automatic brain tumour diagnostic classifiers which were trained on databases of 1.5T spectra. This will allow the existing large databases of 1.5T MRS data to be used for diagnostic classification of 3T spectra, and perhaps also the combination of 1.5T and 3T databases.(More)
Low biomedical Data Quality (DQ) leads into poor decisions which may affect the care process or the result of evidence-based studies. Most of the current approaches for DQ leave unattended the shifting behaviour of data underlying concepts and its relation to DQ. There is also no agreement on a common set of DQ dimensions and how they interact and relate to(More)
The incorporation of new biomedical technologies in the diagnosis and prognosis of cancer is changing medicine to an evidence-based diagnosis. We summarize some studies related to brain tumour research in Europe, based on the metabolic information provided by in vivo Magnetic Resonance Spec-troscopy (MRS) and transcriptomic profiling observed by DNA(More)
The success of Clinical Decision Support Systems (CDSS) greatly depends on its capability of being integrated in Health Information Systems (HIS). Several proposals have been published up to date to permit CDSS gathering patient data from HIS. Some base the CDSS data input on the HL7 reference model, however, they are tailored to specific CDSS or clinical(More)
Diabetes Mellitus (DM) affects hundreds of millions of people worldwide and it imposes a large economic burden on healthcare systems. We present a web patient empowering system (PHSP4) that ensures continuous monitoring and assessment of the health state of patients with DM (type I and II). PHSP4 is a Knowledge-Based Personal Health System (PHS) which(More)