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  • Alvaro Yogi, Glaucia Elena Callera, +6 authors Carlos Renato Tirapelli
  • Chemistry, Medicine
  • Toxicology and applied pharmacology
  • 2012 (First Publication: 1 November 2012)
  • Ethanol intake is associated with increase in blood pressure, through unknown mechanisms. We hypothesized that acute ethanol intake enhances vascular oxidative stress and induces vascular dysfunctionExpand
  • Patrícia Passaglia, Carla Speroni Ceron, André de Souza Mecawi, Jose Antunes-Rodrigues, Eduardo Barbosa Coelho, Carlos Renato Tirapelli
  • Medicine, Chemistry
  • Vascular pharmacology
  • 2015 (First Publication: 1 November 2015)
  • OBJECTIVES We hypothesized that chronic ethanol intake enhances vascular oxidative stress and induces hypertension through renin-angiotensin system (RAS) activation. METHODS AND RESULTS Male WistarExpand
  • Carlos Renato Tirapelli, Débora Arcieri Casolari, +5 authors Ana Maria de Oliveira
  • Chemistry, Medicine
  • British journal of pharmacology
  • 2005 (First Publication: 1 November 2005)
  • We aimed to functionally characterize endothelin (ET) receptors in the rat carotid artery. mRNA and protein expressions of both ETA and ETB receptors, evaluated by reverse transcription-polymeraseExpand
    AIMS Investigate the role of NADPH oxidase on ethanol-induced hypertension and vascular oxidative stress. METHODS Male Wistar rats were treated with ethanol (20% v/v). RESULTS Apocynin (10Expand
  • Carlos Renato Tirapelli, Sérgio Ricardo Ambrósio, Fernando B Da Costa, Silvia T Coutinho, Dionéia Camilo Rodrigues de Oliveira, Ana Maria de Oliveira
  • Chemistry, Medicine
  • European journal of pharmacology
  • 2004 (First Publication: 1 May 2004)
  • The present work describes the mechanisms involved in the vasorelaxant effect of the diterpene ent-kaur-16-en-19-oic acid (kaurenoic acid). Kaurenoic acid (10, 50 and 100 microM)Expand
  • S Y Fukada, Carlos Renato Tirapelli, Márcio A F de Godoy, Ana Maria de Oliveira
  • Chemistry, Medicine
  • Journal of cardiovascular pharmacology
  • 2005 (First Publication: 1 February 2005)
  • It has been suggested that low concentrations of angiotensin II cause vasoconstriction, whereas high concentrations evoke vasodilation. Thus, this work aimed to characterize functionally theExpand