Carlos Negreira

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The accumulation of misfolded proteins is associated with various neurodegenerative conditions. Mutations in PMP-22 are associated with the human peripheral neuropathy, Charcot-Marie-Tooth Type 1A (CMT1A). PMP-22 is a short-lived 22 kDa glycoprotein, which plays a key role in the maintenance of myelin structure and compaction, highly expressed by Schwann(More)
This work was carried out in a Uruguayan (South American) population to characterize aging-associated physiological arterial changes. Parameters markers of subclinical atherosclerosis and that associate age-related changes were evaluated in healthy people. A conservative approach was used and people with nonphysiological and pathological conditions were(More)
Achieving accurate measurements of inflammation levels in tissues or thickness changes in biological membranes (e.g., amniotic sac, parietal pleura) and thin biological walls (e.g., blood vessels) from outside the human body, is a promising research line in the medical area. It would provide a technical basis to study the options for early diagnosis of some(More)
By locally measuring changes on arterial wall thickness as a function of pressure, the related Young modulus can be evaluated. This physical magnitude has shown to be an important predictive factor for cardiovascular diseases. For evaluating those changes, imaging segmentation or time correlations of ultrasonic echoes, coming from wall interfaces, are(More)
Biological phantoms are commonly used on biomedical ultrasound research, but they have some limitation. We have been studying the acoustic and thermal properties of polyvinyl chloride-plastisol (PVCP) that have longer time stability. We estimated thermal conductivity in steady-state methods and specific heat with Method of Mixture. PVCP blocks were made(More)
  • César Alexandre, Domingues Teixeira, Maria Da, Graça Cristo, Dos Santos, Lopes Ruano +11 others
  • 2007
Linear versus non-linear noninva-sive temperature prediction in a homogeneous medium subjected to physiotherapeutic ultrasound Comparação entre predição linear e não linear não-invasiva de temper-atura num meio homogêneo sujeito a ultra-som de terapia Abstract The lack of accurate time-spatial temperature estimators/predic-tors conditions the safe(More)
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