Carlos Labrandero

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INTRODUCTION AND OBJECTIVES Tricuspid annular plane systolic excursion (TAPSE) is an echocardiographic measure that allows us to assess right ventricular systolic function. TAPSE measurement is common in adults but reference values for children are scarce. Our objective was to establish reference values for TAPSE in Spanish children and to determine the(More)
Background:Inodilators are routinely used in cardiovascular surgery with cardiopulmonary bypass (CPB). Information regarding safety and tolerability of the novel molecule, levosimendan (LEVO), in newborns is anecdotal; no pharmacokinetic data in this population are available.Methods:This was a phase I, randomized, and blinded study. Neonates undergoing(More)
Background: Neonates are at particular risk of suffering surgery-related LCOS, characterized by impaired myocardial contractility and the peripheral effects of ischemia/reperfusion on endothelium. INDs are strongly recommended although based on suboptimal studies.Aims: Systematic approach to dose-dependent haemodynamic effects of continuous i.v. infusion of(More)
Congenital mitral valve disease is an uncommon condition. Medical treatment can be very complicated in some cases, leaving surgery as the only option. Surgical valvuloplasty often fails in children, especially in neonates and young infants, due to the presence of dysplastic valves with a small annulus and special anatomic features. In such cases, valve(More)
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