Carlos J. Corrada Bravo

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Many research groups have described genetic networks as networks of Boolean variables. We will show that these Boolean network models are examples of Finite Dynamical Systems (FDS), and we will generalize Boolean networks to finite fields, which we call finite field genetic network models. We also show two different methods to construct these FDS models(More)
1. Santoro, B. & Tibbs, G. R. The HCN gene family: molecular basis of the hyperpolarization-activated pacemaker channels. Ann. NY Acad. Sci. 868, 741–764 (1999). 2. DiFrancesco, D. Pacemaker mechanisms in cardiac tissue. Annu. Rev. Physiol. 55, 455–472 (1993). 3. Pape, H. C. Queer current and pacemaker: the hyperpolarization-activated cation current in(More)
BACKGROUND Persulfate salts have been identified as a cause of occupational asthma (OA). The aim of the present study was to describe the clinical characteristics, diagnostic testing results, and follow-up of eight patients with OA that was triggered by these chemical compounds. METHODS Eight patients with OA due to exposure to persulfate salts were(More)
BACKGROUND Lung transplant recipients may have pleural complications. However, the influence of these complications on the prognosis is not well known. METHODS We analyzed pleural complications and clinical and radiologic data from 100 patients who underwent lung transplantation in a general hospital in a 9-year period. Pre-operative evaluation, surgical(More)
Seventy-six cytomegalovirus (CMV)-seropositive lung transplant recipients receiving valganciclovir (900 mg/day) for CMV prophylaxis were compared with a group of 87 patients receiving oral ganciclovir (3000 mg/day). Prophylaxis was administered to day 120 post-transplantation and follow-up was 1 year. In addition, a study was conducted on risk factors for(More)
BACKGROUND The aim is to correlate pulmonary arterial (PA) remodeling estimated by PA fibrosis in PA hypertension (PAH) with clinical follow-up. Histology of PA specimens is also performed. METHODS 19 patients, aged 54±16 (4 men), functional class II-III were studied with right heart catheterization, PA Intravascular Ultrasound and optical coherence(More)
The aim of this study was to determine whether cyclosporine levels predose (C0) and at two hours postdose (C2) were higher among patients presenting with cytomegalovirus (CMV) infection or disease. Between days 40 and 365 posttransplantation serial C0 and C2 levels were measured in 15 lung transplant recipients. Nine developed 13 episodes of CMV infection(More)
BACKGROUND Chronic obstructive pulmonary disease is the primary indication for lung transplantation worldwide. In this study, we analyzed the early outcomes of patients with emphysema undergoing bilateral lung transplantation at our center. METHODS This retrospective analysis included 79 consecutive bilateral lung transplantation performed due to(More)
BACKGROUND The Nissen fundoplication procedure is the most widely used type of antireflux surgery. The results are not always as good as expected, and several modifications to the original technique have been proposed. Long-term effectiveness studies comparing different techniques of antireflux surgery are limited. Our group developed a new concept in(More)