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  • Sol Cristians, José A. Guerrero-Analco, +4 authors Rachel Mata
  • Medicine, Chemistry
  • Journal of natural products
  • 2009 (First Publication: 27 March 2009)
  • The CH(2)Cl(2)-MeOH (1:1) extract of the leaves of Hintonia standleyana and H. latiflora caused significant decrease in blood glucose levels in both normal and streptozotozin (STZ)-induced diabeticExpand
  • Angel H Romero, Rafael Medina, +7 authors Simón E. López
  • Medicine, Chemistry
  • European journal of medicinal chemistry
  • 2017 (First Publication: 15 February 2017)
  • With the aim to identify a potential drug candidate to treat cutaneous leishmaniasis, a series of 1-phthalazinyl hydrazones were synthesized and tested against Leishmania braziliensis parasite, oneExpand
  • Edgar A. Valverde, Angel H Romero, +5 authors Simón E. López
  • Medicine, Chemistry
  • European journal of medicinal chemistry
  • 2018 (First Publication: 18 October 2017)
  • Many people are affected by Malaria around the world, and the parasite is developing resistance against available drugs. Currently, isoquine and N-tert-butyl isoquine are some of the most promisingExpand
  • J D Suarez-Torres, Carlos E Ciangherotti, Fausto A Jimenez-Orozco
  • Medicine
  • Journal of pharmacological and toxicological…
  • 2020 (First Publication: 12 March 2020)
  • The pre-marketing testing of drugs and chemicals is now a paradigm of contribution to the safeguard of public health. As pointed out by the ICH concept paper E14/S7B, there is a need forExpand
  • Yosmery Vitta, Maice Figueroa, María José Gómez Calderón, Carlos E Ciangherotti
  • Chemistry
  • 2020 (First Publication: 1 November 2019)
  • Abstract In this work we obtained iron nanoparticles (FeNP) from the aqueous extract of the leaves of E. robusta and to evaluate their antimicrobial activity on different pathogenic microorganisms.Expand
  • J D Suarez-Torres, Fausto A Jimenez-Orozco, Carlos E Ciangherotti
  • Chemistry, Medicine
  • Toxicology mechanisms and methods
  • 2020 (First Publication: 25 April 2020)
  • Abstract The long-term rodent bioassay (RCB) has been the gold-standard for the pre-marketing prediction of chemical and drug carcinogenicity to humans. Nonetheless, the validity of this toxicityExpand
    La diabetes es uno de los principales problemas de salud publica mundial. Las complicaciones tisularesde la diabetes es su principal causa de muerte, siendo la nefropatia diabetica la que lidera laExpand