Carlos César Pérez

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In this study we determined the norepinephrine (NE), epinephrine and methoxy-hydroxy-phenyl-glycol (MHPG) levels in dissected chick telencephalon, diencephalon/mesencephalon and cerebellum in a number of stages from the late embryonic period (E16, E17, E18 and E19) and post-hatching period (P1, P2, P3, P4, P5, P15 and P30) using HPLC coupled with a(More)
Here we studied muscarinic receptors in the gerbil thalamus at 8 different ages - from 6 to 36 months - using receptor and functional autoradiography. The pharmacological profile inhibiting [(3)H]N-methyl scopolamine ([(3)H]NMS) binding with 50 and 200 nM pirenzepine, 30 nM pFHHSiD and 100 nM AF-DX 116 revealed the predominance of the M(2) muscarinic(More)
In this work, we studied the in vitro G-protein activation induced by muscarinic agonists using [(35)S]guanylyl-5'-O-(gamma-thio)-triphosphate ([(35)S]GTPgammaS) autoradiographic methods to characterize the M(2) and M(4) muscarinic subtypes response. Thus, we describe a detailed characterization of the increases in [(35)S]GTPgammaS binding elicited by(More)
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