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BACKGROUND We conducted a study of congenital Trypanosoma cruzi infection in Santa Cruz, Bolivia. Our objective was to apply new tools to identify weak points in current screening algorithms, and find ways to improve them. METHODS Women presenting for delivery were screened by rapid and conventional serological tests. For infants of infected mothers,(More)
BACKGROUND Patients with Chagas disease have migrated to cities, where obesity, hypertension and other cardiac risk factors are common. METHODOLOGY/PRINCIPAL FINDINGS The study included adult patients evaluated by the cardiology service in a public hospital in Santa Cruz, Bolivia. Data included risk factors for T. cruzi infection, medical history,(More)
BACKGROUND Congenital transmission is a major source of new Trypanosoma cruzi infections, and as vector and blood bank control continue to improve, the proportion due to congenital infection will grow. A major unanswered question is why reported transmission rates from T. cruzi-infected mothers vary so widely among study populations. Women with high(More)
Cooperation incentives are essential in user-centric networks to motivate users to share services and resources (including bandwidth, computational power, and storage space) and to avoid selfish nodes to hinder the functioning of the entire system. Virtual currency and reputation mechanisms are commonly adopted in online communities to boost participation,(More)
Trypanosoma cruzi polymerase chain reaction (PCR) is widely used, but sensitivity varies widely. We compared PCR using 121/122 primers targeting kinetoplast minicircle DNA in whole blood, buffy coat, and clot from Bolivian women. Sensitivity was significantly higher in clot (60.1%) than buffy coat (46.5%) or whole blood (40%). The use of clot could simplify(More)
Both free and low-priced mobile wireless networks are expanding and its users are more numerous every day. This success is particularly due to the mobility offered to users. These networks have promoted and widespread the success and availability of mobile devices and their access technologies such as Wi-Fi, WiMAX and Bluetooth. Nevertheless, despite of(More)
BACKGROUND We studied women and their infants to evaluate risk factors for congenital transmission and cardiomyopathy in Trypanosoma cruzi-infected women. METHODS Women provided data and blood for serology and quantitative polymerase chain reaction (PCR). Infants of infected women had blood tested at 0 and 1 month by microscopy, PCR and immunoblot, and(More)
Chagas disease affects 8-11 million people throughout the Americas. Early detection is crucial for timely treatment and to prevent non-vectorial transmission. Recombinant antigen-based rapid tests had high sensitivity and specificity in laboratory evaluations, but no Peruvian specimens were included in previous studies. We evaluated Stat-Pak and Trypanosoma(More)
Wireless networks today are partially being formed by nodes (e.g. Internet access points, smartphones, femtocells)that are owned and carried by humans. In such scenarios where several strangers are expected to interact for the sake of robust data transmission, trust and reputation are of vital importance. As such, User Centric Networks require well-defined(More)
During the last few years the amount of users with mobile devices (laptops, smart phones, tablets, etc.) with wireless connectivity capabilities has grown at an impressive rate. In the meantime, the number of Wi-Fi networks has also increased a lot, and in addition to this, the emergence and fast growth of applications such as social networking, user(More)