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OBJECTIVES To investigate whether a disease-specific nutritional approach is more beneficial than a standard dietary approach to the healing of pressure ulcers (PUs) in institutionalized elderly patients. DESIGN Twelve-week follow-up randomized controlled trial (RCT). SETTING Four long-term care facilities in the province of Como, Italy. PARTICIPANTS(More)
The American Academy of Neurology suggests advising the redistribution of daily protein meal content to every Parkinson's disease (PD) patient with motor fluctuations during levodopa treatment. However, no comprehensive evaluation of this complementary therapy has been performed. A systematic review of intervention studies investigating the neurologic(More)
Chronic activation of the inflammatory response, defined as inflammaging, is the key physio-pathological substrate for anabolic resistance, sarcopenia and frailty in older individuals. Nutrients can theoretically modulate this phenomenon. The underlying molecular mechanisms reducing the synthesis of pro-inflammatory mediators have been elucidated,(More)
OBJECTIVE Malnutrition and sarcopenia in institutions are very common and significantly affect the prognosis. Aging is characterized by weight and lean body mass losses. Accordingly, in elderly patients, body mass index (BMI) is considered a marker of protein stores rather than of adiposity. Current guidelines suggest a BMI 21 kg/m(2) or lower as major(More)
BACKGROUND & AIMS A new tool, the Geriatric Nutritional Risk Index (GNRI), was recently proposed to predict short-term complications in elderly medical patients but no information is available when long-term follow-up periods are considered. METHODS A 3-year follow-up study in 245 institutionalised elderly (51 M:194 F; 83.7+/-8.6 years). Nutritional risk(More)
PURPOSE OF REVIEW A new nutrition-related risk assessment tool, the Geriatric Nutritional Risk Index (GNRI), has been recently proposed. The aim of this review is to summarize current evidences on the use of this tool with particular focus on the rationales of its application in elderly healthcare. RECENT FINDINGS Structured as a dichotomous index, based(More)
BACKGROUND & AIMS To possibly validate the use of Mini Nutritional Assessment (MNA) with respect to functional status in institutionalised elderly. METHODS One hundred twenty-three long-term care resident elderly (85.3+/-8.4 years) were recruited. Nutritional and functional states were assessed by MNA and Barthel Index (BI), respectively. Main inclusion(More)
Previous studies have reported a close relationship between nutritional and functional domains, but evidence in long-term care residents is still limited. We evaluated the relationship between nutritional risk and functional status and the association of these two domains with mortality in newly institutionalised elderly. In the present multi-centric(More)
BACKGROUND & AIMS Several tools are available for nutritional screening. We evaluated the risk of mortality associated with the Geriatric Nutritional Risk Index (GNRI) and the Mini Nutritional Assessment (MNA) in newly institutionalised elderly. METHODS A prospective observational study involving 358 elderly newly admitted to a long-term care setting.(More)
OBJECTIVE Diabetes has been associated with chronic neurodegeneration. We performed a systematic review and meta-analysis to assess the relationship between pre-existing diabetes and Parkinson's disease (PD). RESEARCH DESIGN AND METHODS Original articles in English published up to 10 May 2011 were searched for in electronic databases (PubMed, Embase, and(More)