Carlo Hamm

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INTRODUCTION Bipolar disorder (BD) is a chronic psychiatric disease which can take most different and unpredictable courses. It is accompanied by unspecific brainstructural changes and cognitive decline. The neurobiological underpinnings of these processes are still unclear. Emerging evidence suggests that tryptophan catabolites (TRYCATs), which involve all(More)
INTRODUCTION Bipolar disorder (BD) is accompanied by a high number of comorbidities and associated with an overall increased mortality. Especially obesity, systemic inflammatory processes and cognitive deficits are highly prevalent and increase with the course of illness. Physical activity (PA) is associated with beneficial effects on somatic comorbidities(More)
INTRODUCTION It has been demonstrated that bipolar disorder (BD) is often accompanied by cognitive deficits across all subdomains including verbal memory, attention and executive functioning. Cognitive deficits are observed both during episodes of mania or depression, as well as during the euthymic phase. It has been proposed that chronic immune-mediated(More)
prognosis are determined by a multitude of factors that include, but are not limited to, age; stage of cancer; tumour characteristics such as estrogen receptor (er) status, progesterone receptor (pr) status, and human epidermal growth factor receptor 2 (her2/ neu) status; and histologic grade. Gene expression profiling has revealed new classifications of(More)
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